中国医药科学2016，Vol.6Issue(14)：13-17,23,6.
尘螨过敏原环境干预提高哮喘儿童肺功能及生活质量
Dust mite allergen environmental intervention to improve pulmonary function and quality of life in children with asthma
祁姗姗 1祝戎飞 1黄南 1李文静 1刘光辉1
作者信息
- 1. 华中科技大学同济医学院附属同济医院过敏反应科，湖北武汉 430030
- 折叠
摘要
Abstract
Objective To assess the relationship between 2 kinds of dust mite allergen exposure intervention and Control level of asthma in children.Methods45 children with asthma were enrolled and divided into 3 groups: group A with no intervention, group B with new mattress, quilts, pillows and sofa cushion, group C with old mattress, quilts, pillows and sofa cushion. Dust samples of bed mattress, quilt, pillow and sofa in children's home were collected separately on 3 months, 6 months and 12 months before and after the intervention. Enzyme linked immunosorbent assay (ELISA) was used to determine the content of dust mite allergens in dust sample components (Der p1 and Der f1), to measure and record children asthma control test (ACT/C-ACT) score and peak expiratory flow rate in the patients with PEF.Results3, 6 and 12 months after Environmental intervention, dust mite allergen levels in the family of intervention group was significantly lower than that of children with no intervention (lower than 10 μg/g, P<0.05). Dust mite allergen content in mattress and quilt in one year after intervention was negatively correlated with ACT/C-ACT score. Dust mite allergen levels in sofa and mattress was negatively correlated with children PEFR.ConclusionChanging of bedding items for new or using anti-mite sets allows a reduction of mite allergen concentration. It can significantly reduce indoor dust mite allergen exposure level, improve the symptoms of asthma in children, and reduce airway hyper reactivity.关键词
儿童/哮喘/尘螨/环境干预Key words
Children/Asthma/Dust mite/Environmental intervention分类
医药卫生引用本文复制引用
祁姗姗,祝戎飞,黄南,李文静,刘光辉..尘螨过敏原环境干预提高哮喘儿童肺功能及生活质量[J].中国医药科学,2016,6(14):13-17,23,6.
