中国医药科学2016，Vol.6Issue(14)：31-34,4.
容积调强技术在食管癌放疗中的剂量学研究
Dosimetric study on the volumetric modulated arc therapy in the radiotherapy of esophageal cancer
摘要
Abstract
ObjectiveTo explore the dosimetric differences between volumetric modulated arc therapy (VMAT) and intensity modulated radiation therapy (IMRT) in the radiotherapy of esophageal cancer. Methods30 patients with esophageal cancers during June 2014 and August 2015 were recruited. The single arc VMAT (Arc 1) plan, double arc VMAT (Arc2) plan, and IMRT 9 fields plan were designed by Varian Eclipse 10.0 planning system. The dosimetric differences of average dose volume histogram, target section dose distribution, organ damage, and normal tissue protections of the three plans were compared. The total monitor unit (MU) numbers and treatment time of the three plans were compared.ResultsThe homogeneity index (HI) and conformal index (CI) of VMAT (Arc2) plan were better than the other two plans (P<0.05). In terms of organ damage, the VMAT (Arc2) plan's Dmax protections of double lung and spinal cord were better than those of VMAT (Arc1) plan, the VMAT(Arc2) plan's Dmean protection of heart and Dmax protection of spinal cord were better than those of IMRT 9 fields. In terms of treatment time, the VMAT (Arc1) plan needed the shortest time—evenly 90 seconds, the VMAT (Arc2) plan lasted for 190 to 200 seconds, and IMRT 9 fields evenly lasted for 680 seconds.Conclusion All the VMAT (Arc1) plan, VMAT (Arc2) plan and IMRT 9 fields plan can satisfy the clinical dosimetric requirements, while the VMAT (Arc2) is more common for clinical practice according to Varian Eclipse 10.0 planning system.关键词
放射治疗/食管癌/容积旋转调强/静态调强/剂量学Key words
Radiotherapy/Esophageal cancer/Volumetric modulated arc therapy/Intensity modulated radiation therapy/Dosimetric medicine分类
医药卫生引用本文复制引用
余建荣,古定标,李珍,郭纪慈..容积调强技术在食管癌放疗中的剂量学研究[J].中国医药科学,2016,6(14):31-34,4.基金项目
广东省中山市医学科研项目（2014J001）。 （）
