中国医药科学2016，Vol.6Issue(14)：52-54,58,4.
阿德福韦酯治疗慢性乙肝临床分析
Clinical analysis of adefovir dipivoxil in the treatment of chronic hepatitis B
史保生1
作者信息
- 1. 河南省鹤壁市传染病医院肝炎科，河南鹤壁 458000
- 折叠
摘要
Abstract
Objective To analyze the clinical effect of adefovir dipivoxil in the treatment of chronic hepatitis B. Methods112 cases of patients with chronic hepatitis B treated in our hospital from June 2011 to September 2014 were selected and divided into the control group and the observation group according to the digital random table with 56 cases in each. The treatment was divided into two phases, the first phase was 12 weeks, and the second stage was 36 weeks. Patients in the control group in first stage were treated with placebo, and patients in the second phase were treated with adefovir dipivoxil. Patients in the observation group were treated with adefovir dipivoxil all along. The effects between the two groups were compared at the end of the first stage and the end of the second stage.Results At the end of the first stage, the serum HBV-DNA and baseline comparison of two groups were significantly different (P<0.05), and the level of HBV-DNA of the observation group was significantly lower than that of the control group (P<0.05). At the end of the second stage, serum HBV-DNA levels of the two groups were decreased significantly (P<0.05). The patients were compared between the two groups, whose serum HBV-DNA were more than or equal to 2log10, and there was no significant difference in baseline values (P>0.05).Conclusion Using the adefovir dipivoxil to treat chronic hepatitis B, the effect is significant, the security is high, and it is worth popularizing and applying.关键词
阿德福韦酯/安慰剂/慢性乙肝/疗效/临床分析Key words
Adefovir dipivoxil/Placebo/Chronic hepatitis B/Effect/Clinical analysis分类
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史保生..阿德福韦酯治疗慢性乙肝临床分析[J].中国医药科学,2016,6(14):52-54,58,4.
