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甲氨蝶呤不同用药途径治疗瘢痕妊娠疗效比较

曾人宏 詹伦娟 朱莉

中国医药科学2016,Vol.6Issue(14):55-58,4.
中国医药科学2016,Vol.6Issue(14):55-58,4.

甲氨蝶呤不同用药途径治疗瘢痕妊娠疗效比较

Comparative study on curative effect of different ways of using methotrexate in treatment of scar pregnancy

曾人宏 1詹伦娟 1朱莉1

作者信息

  • 1. 广东省惠州市第一妇幼保健院,广东惠州 516000
  • 折叠

摘要

Abstract

Objective To explore the clinical efficacy of different ways of using methotrexate in treatment of scar pregnancy for reference and research.Methods98 cases of patients with scar pregnancy cured in our hospital from July 2014 to October 2015 were selected as the study objects and divided in to two groups according to dynamic random grouping method. 49 cases were divided into control group and treated with methotrexate injection route, and 49 cases were divided into observation group and treated with methotrexate uterine artery chemoembolization route. The otherness of clinical correlation index (blood β-HCG recovery time, the gestational sac disappear time, postoperative time of vaginal bleeding, menstrual recovery time, hospitalization time,, adnexal mass disappeared time), adverse drug reactions (abdominal pain, nausea, uterine rupture) and the number of cured cases after the implementation of different routes of administration were explored.Results Through the research of this paper can be seen as follows: On the comparison of clinical correlation index (blood β-HCG recovery time, the gestational sac disappear time, postoperative time of vaginal bleeding, menstrual recovery time, hospitalization time, adnexal mass disappeared time), adverse drug reactions (abdominal pain, nausea, uterine rupture) and the number of cured cases, the results of observation group were significantly better than those of control group, and the differences were statistically significant(P<0.05).Conclusion Methotrexate uterine artery chemoembolization route in treatment of patients with scar pregnancy has better clinical efficacy. It can effectively alleviate the clinical symptoms of patients to a certain extent with lower incidence of adverse reactions. It is safe and effective. Treatment time is short. It is worthy of clinical application and promotion.

关键词

甲氨蝶呤/不同用药途径/瘢痕妊娠

Key words

Methotrexate/Different ways of drug administration/Scar pregnancy

分类

医药卫生

引用本文复制引用

曾人宏,詹伦娟,朱莉..甲氨蝶呤不同用药途径治疗瘢痕妊娠疗效比较[J].中国医药科学,2016,6(14):55-58,4.

中国医药科学

2095-0616

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