中国肿瘤生物治疗杂志2016,Vol.23Issue(4):453-467,15.DOI:10.3872/j.issn.1007-385X.2016.04.001
曲妥珠单抗的耐药机制及其逆转策略
Mechanism of trastuzumab resistance and strategies to overcome the resistance
摘要
关键词
曲妥珠单抗/耐药/乳腺癌/人表皮生长因子受体2/磷脂酰肌醇-3激酶Key words
trastuzumab/drug resistance/breast carcinoma/human epidermal growth factor receptor 2 (HER2)/phosphotidylinositol 3-kinase(PI3K)分类
医药卫生引用本文复制引用
刘丹,刘彦君,施明..曲妥珠单抗的耐药机制及其逆转策略[J].中国肿瘤生物治疗杂志,2016,23(4):453-467,15.基金项目
国家重大新药创制资助项目(No.2013ZX09102056) (No.2013ZX09102056)
国家高技术研究发展计划(863计划)资助项目(No.2014AA020604) (863计划)
国家自然科学基金资助项目(No.31370825,81272232,81402562,81572845,81401311,31500702) (No.31370825,81272232,81402562,81572845,81401311,31500702)
国家博士后基金资助项目(No.2015T81095) (No.2015T81095)
北京市自然科学基金资助项目(No.7122124,7132163). Project supported by the National Key Technologies R&D Program for New Drugs (No.2013ZX09102056),the National High-Tech R&D Program of China (863 Program) (No.2014AA020604),the National Natural Science Foundation of China (No.31370825,81272232,81402562,81572845,81401311,31500702),the National Postdoctoral Science Foundation of China (No.2015T81095),and the Beijing Natural Science Foundation of China(No.7122124,7132163) (No.7122124,7132163)