中国现代中药2016，Vol.18Issue(7)：907-912,6.DOI:10.13313/j.issn.1673-4890.2016.7.023
响应曲面法优化金花葵种子中黄酮的提取工艺
Optimization of Extraction Parameters of Flavonoids from Ablemoschus manihot Using Response Surface Methodology
摘要
Abstract
Objective: To optimize the process of extracting flavonoids from the seeds of Ablemoschus manihot.Methods:Ethanol concentration,extraction time and liquid ratio were selected as independent variables of response surface methodology to study the effects of various factors and their interactions on extraction of flavonoids from the seeds of A.manihot.The extraction regression equation for flavonoids was obtained by simulation and the optimum extraction conditions of flavonoids were determined.Results:The optimal extraction parameters were as follows:ethanol concentration 60%, extraction temperature 80 ℃,extraction time 60 min,liquid ratio 1 ∶39.Conclusion:The extraction technology is reliable, reasonable and highly predictive.关键词
金花葵/黄酮/响应曲面/乙醇提取/紫外分光光度法Key words
Ablemoschus manihot/flavonoid/response surface/alcohol extracting/ultraviolet spectroscopy引用本文复制引用
王璐珊,吴士龙,王淼,李先哲,王达,吴兆华,高慧媛..响应曲面法优化金花葵种子中黄酮的提取工艺[J].中国现代中药,2016,18(7):907-912,6.基金项目
沈阳药科大学药物化学学科建设研究资助计划，校级优秀中青年教师资助计划A类 （）
