中国当代医药2016，Vol.23Issue(19)：23-25,32,4.
和肽素、乳酸及D-二聚体对呼吸机相关性肺炎预后评估的研究
Study the prognostic evaluation of peptide hormone,lactic acid and D-dimer in ventilator associated pneumonia
摘要
Abstract
Objective To explore the value of peptide hormone,lactic acid and D-dimer in prognostic evaluation of ven-tilator associated pneumonia.Methods 50 patients with ccute exacerbation of chronic obstructive pulmonary disease combined with respiratory failure,cerebral apoplexy and saltwater drowning that needed mechanical ventilation therapy, from May 2015 to May 2016 of respiration department and ICU of our hospital were selected.Patients were divided into ventilator associated pneumonia (VAP group,n=29) and non ventilator associated pneumonia (non VAP group,n=21) ac-cording to the diagnostic criteria of ventilator associated pneumonia.According to the prognosis of patients,the 10 death patients of VAP group were divided into death group and 19 improvement patients were divided into survival group.The level of peptide hormone,lactic acid and D-dimer in each group were tested,and the relationship between the three in-dex and ventilator associated pneumonia was studied.Results The peptide hormone,lactic acid,D-dimer,PCT,APACHEⅡin VAP group was obvious higher than that of non VAP group respectively(P﹤0.05);The peptide hormone,lactic acid, D-dimer,PCT,APACHEⅡ in survival group was obvious lower than that of death group respectively(P﹤0.05);The suscepti-bility of peptide hormone,lactic acid and D-dimer in VAP was lower than PCT in death group,and all of them had higher susceptibility.Conclusion Peptide hormone,lactic acid and D-dimer are powerful predictive factor of ventilator associated pneumonia death,which is helpful to guide the clinical evaluation of the patients'risk.关键词
和肽素/乳酸/D-二聚体/呼吸机相关性肺炎Key words
Peptide hormone/Lactic acid/D-dimer/Ventilator associated pneumonia分类
医药卫生引用本文复制引用
周晖东,晏斌林,杜娟..和肽素、乳酸及D-二聚体对呼吸机相关性肺炎预后评估的研究[J].中国当代医药,2016,23(19):23-25,32,4.基金项目
名称]广东省深圳市盐田区科技计划项目(20150103) （20150103）
