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简易精神状态量表评分正常慢性阻塞性肺疾病患者脑认知功能研究

汪春荣 邱士军 沈比先 高德宏 邹立秋 谭四平 褚千琨

中国当代医药2016,Vol.23Issue(19):36-39,4.
中国当代医药2016,Vol.23Issue(19):36-39,4.

简易精神状态量表评分正常慢性阻塞性肺疾病患者脑认知功能研究

The study of brain cognitive function in patients with chronic obstructive pulmonary disease with normal mini-mental state examination scores

汪春荣 1邱士军 2沈比先 1高德宏 1邹立秋 1谭四平 1褚千琨1

作者信息

  • 1. 广东医学院附属南山医院影像科,深圳 518052
  • 2. 广州中医药大学第一附属医院影像科,广州 510405
  • 折叠

摘要

Abstract

Objective To investigate whether there is brain cognitive impairment in patients with chronic obstructive pulmonary disease(COPD) whose mini-mental state examination(MMSE) score are normal.Methods Sixty patients with stable COPD whose MMSE score were normal in our hospital and sixty normal controls from the local community from July 2012 to March 2015 were recruited.All subjects were assessed with the montreal cognitive assessment scale(MoCA) including visuospatial and executive function,naming ability,attention,language fluency,abstraction,memory and orienta-tion.The differences of the MoCA scores were analyzed and compared respectively between two groups.Results The MMSE total score,MoCA total score of COPD patients was lower that in normal controls respectively with statistical dif-ference(P﹤0.05).Visuospatial and executive function(P=0.028),naming ability(P=0.024) and memory(P﹤0.001) were sig-nificantly worse in COPD than normal controls,but there were no significant differences in attention, language fluency, abstraction,orientation.Conclusion There is still brain cognitive impairment of the patients with COPD whose MMSE score are normal.It is better to use MoCA than MMSE screening COPD patients in cognitive impairment.

关键词

慢性阻塞性肺疾病/简易精神状态量表/蒙特利尔认知评估量表/脑认知障碍

Key words

Chronic obstructive pulmonary disease(COPD)/Mini-mental state examination(MMSE)/Montreal cognitive assessment scale(MoCA)/Brain cognitive impairment

分类

医药卫生

引用本文复制引用

汪春荣,邱士军,沈比先,高德宏,邹立秋,谭四平,褚千琨..简易精神状态量表评分正常慢性阻塞性肺疾病患者脑认知功能研究[J].中国当代医药,2016,23(19):36-39,4.

中国当代医药

1674-4721

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