检验医学与临床2016，Vol.13Issue(15)：2084-2086,2089,4.DOI:10.3969/j.issn.1672-9455.2016.15.005
脂肪负荷餐对肝功能指标的影响
Impact of fat load meal on liver function indices
摘要
Abstract
Objective To evaluate the impact of the fat load meal on the liver function biochemical indices and to explore the fea‐sibility of using non‐fasting blood for conducting the liver function test .Methods Using the self controlled trial design ,the blood samples from 603 subjects at fasting and at 2 ,4 ,6 ,8 h after the fat load meal were collected to detect the liver function biochemical indices and the changes of liver function indices were compared between before and after meal .Results The changed amplitudes of liver function indices at different time points were very small ,moreover the majority were postprandial slight decreases .The impact of fat load meal on the changes of postprandial liver function indices had no statistical differences between the youth group and mid‐dle age group ,between the male group and female group ,between the fasting blood lipid normal group and abnormal group(P>0 .05) .The impact of fat load meal on the changes of postprandial DBiL ,ALT ,AST and γ‐GT had statistical differences between the normal and the abnormal liver function groups(P<0 .05) .But the detection values in the liver function normal group and abnor‐mal groups had no statistical differences between at fasting and at postprandial 2 ,4 ,6 h(P>0 .05) ,therefore these changes could be considered as no clinical significance and had no impact on the detection results of postprandial liver function indices .Conclusion The fat load meal has no effect on the liver function indices testing ,the liver function test may be carried out at any time .关键词
肝功能指标/脂肪负荷餐/餐前/餐后Key words
liver function indices/fat load meal/before meal/postprandial引用本文复制引用
郑靖,王佑娟,刘雯,舒世清,王颖,朱晓红,苗佳..脂肪负荷餐对肝功能指标的影响[J].检验医学与临床,2016,13(15):2084-2086,2089,4.基金项目
四川省科技厅项目（2011SZ0198，2010SZ0170）。 （）
