检验医学与临床2016，Vol.13Issue(15)：2116-2118,3.DOI:10.3969/j.issn.1672-9455.2016.15.017
全自动血细胞形态学识别系统在恶性血液系统疾病外周血涂片分析中的应用评价
Application evaluation of automatic blood cell morphology recognition system in peripheral blood smear analysis of malignant hematological diseases
唐玉凤 1陈吉祥 1陈勋 1郭慧娟 1郑颖 1王玲玲 1尚晓泓1
作者信息
- 1. 中国中医科学院西苑医院检验科，北京100091
- 折叠
摘要
Abstract
Objective To evaluate the value of the CellaVision DM96(DM96) automatic blood cell morphology recognition sys‐tem in peripheral blood cell smear analysis of malignant hematological diseases .Methods The peripheral blood smear samples in 436 patients with malignant hematological diseases were analyzed on WBC ,nucleated RBC ,mature RBC and platelets by adopting the DM96 with the manual microscopy as the evaluation standard .The ability of DM96 for recognizing 8 abnormalities(abnormal cell or abnormal situation) was evaluated .Results The consistency ,specificity ,sensitivity ,positive predictive value and negative predictive value of DM96 system for identifying abnormal WBC were higher ,especially for primary cells ,which were 98 .4% , 98 .8% ,97 .9% ,98 .4% and 98 .4% respectively .Its sensitivity and positive predictive value for identifying nucleated red blood cells were lower(62 .1% ,72 .7% ) .Its sensitivity for identifying platelet clumps was lower (71 .4% ) .Conclusion The DM96 system is a powerful tool of peripheral blood cell smear analysis ,has higher accuracy in the analysis of WBC ,mature RBC morphology ,but the samples of nucleated RBC and suspected platelet clumps need to be assisted by manual microscopy examination .关键词
血液系统疾病/恶性/白细胞分类/显微镜/细胞形态学Key words
hematological diseases/malignant/leucocyte classification/microscopy/cell morphology引用本文复制引用
唐玉凤,陈吉祥,陈勋,郭慧娟,郑颖,王玲玲,尚晓泓..全自动血细胞形态学识别系统在恶性血液系统疾病外周血涂片分析中的应用评价[J].检验医学与临床,2016,13(15):2116-2118,3.
