检验医学与临床2016，Vol.13Issue(15)：2119-2120,2125,3.DOI:10.3969/j.issn.1672-9455.2016.15.018
喉癌单纯放疗失败后行喉部分切除术的预后研究
Study on prognosis of partial laryngectomy after failure of simple radiotherapy in laryngeal carcinoma
邓玫 1罗伟 1朱力1
作者信息
- 1. 成都医学院第一附属医院耳鼻喉头颈外科，成都610500
- 折叠
摘要
Abstract
Objective To explore the clinical curative effect and prognostic influencing factors of partial laryngectomy in the pa‐tients with recurrent primary laryngeal carcinoma after failure of radiotherapy .Methods The clinical data in 20 cases of recurrent primary laryngeal carcinoma undergoing partial laryngectomy after failure of radiotherapy were retrospectively analyzed .Results Among 20 cases ,the 3‐year overall survival rate was 60 .0% ;which in 15 cases of negative resection margins was 66 .67% ;while which in 5 cases of positive resection margins was 40 .0% ;among 15 cases of negative resection margins ,3 cases(20 .0% ) recurred , in which 2 cases appeared oropharyngeal tumor and 1 case appeared tumor recurrence in situ and lymph node metastasis ,the re‐lapse‐free survival rate was 12 months(5-16 months) and the 2‐year disease‐free survival rate was 66 .7% ;the postoperative cases could pronounced and recovered the swallowing function with normal eating ,the average gastric tube removal time was 13 d (6-50 d);except 3 cases without removing the gastric tube due to partial recurrence and 1 case of difficult gastric tube removal due to radi‐oactive laryngeal edema ,remaining 16 cases succeeded in tube removal ,the tube removal rate was 80 .0% ,the average tube removal time was 16 d(13-124 d) .The UW‐QOL living quality evaluation in 10 screened cases demonstrated that the aspects of pain ,activ‐ity ability ,entertainment ,work ,chewing ,swallowing and talk exchange were improved to some extents .The multivariate analysis indicated that the location of primary carcinoma was the main influencing factor of living quality .Conclusion Conducting partial laryngectomy for recurrent primary laryngeal carcinoma after failure of radiotherapy in the patients with early laryngeal carcinoma could obtain better curative effect .关键词
回顾性分析/喉癌/放疗失败/喉部分切除术Key words
retrospective study/laryngeal carcinoma/failure of radiotherapy/partial laryngectomy引用本文复制引用
邓玫,罗伟,朱力..喉癌单纯放疗失败后行喉部分切除术的预后研究[J].检验医学与临床,2016,13(15):2119-2120,2125,3.
