世界中医药2016，Vol.11Issue(7)：1279-1281,1285,4.DOI:10.3969/j.issn.1673-7202.2016.07.033
黄芪胶囊对桥本氏甲状腺炎患者自身免疫性抗体的影响
Effect of Huangqi Capsule on the Level of Autoimmune Antibodies in Patients with Hashimoto′s Thyroiditis
摘要
Abstract
Objective:To observe the effect of Huangqi capsule on serum thyroid peroxidase antibody ( TPOAb) and thyroglobulin antibody ( TgAb) in patients with Hashimoto′s thyroiditis. Methods:Sixty patients with Hasimoto′s thyroiditis were randomly divid-ed into treatment group (30 cases) and control group (30 cases). The control group only received a low iodine diet,and the treat-ment group accept Huangqi capsule on the basis of low iodine. The duration of treatment was 12 weeks. The change of TPOAb, TgAb,serum free triiodothyronine (FT3),free thyroxine(FT4) and thyroid stimulatting hormone (TSH) were observed after treat-ment. Results:After treatment,the TPOAb and TgAb level were reduced significantly in treatment group (P<0. 01),but there is no difference in the control group. There was no significant difference in FT3,FT4 and TSH in both groups before and after treat-ment (P>0. 05). Conclusion:Huangqi capsule can reduce the TPOAb and TgAb levels of HT patients,and improve the thyroid autoimmune reaction with a favorable clinical effect,with no adverse reactions.关键词
黄芪胶囊/桥本氏甲状腺炎/甲状腺过氧化物酶抗体/甲状腺球蛋白抗体Key words
Huangqi capsule/Hashimoto′s thyroiditis/Thyroid peroxidase antibody/Thyroglobulin antibody分类
医药卫生引用本文复制引用
章丽琼,陆灏,徐佩英..黄芪胶囊对桥本氏甲状腺炎患者自身免疫性抗体的影响[J].世界中医药,2016,11(7):1279-1281,1285,4.基金项目
上海市科学技术委员会科研计划项目(编号:13401903200) （编号:13401903200）
上海市科学技术委员会科研计划项目(编号:14401930600) （编号:14401930600）
