世界中医药2016，Vol.11Issue(7)：1370-1373,4.DOI:10.3969/j.issn.1673-7202.2016.07.057
基于聚类分析探究中药复方治疗肺间质纤维化临床用药规律
Study on Medicinal Rule of Compound Formulas in Treating Idiopathic Pulmonary Fibrosis by Cluster Analysis
摘要
Abstract
Objective:To analyze the experience in using medicine for treating Idiopathic pulmonary fibrosis, and to explore the method for summarizing the experience of famous doctor of TCM. Methods:Sixty-five formulas were included in the study and 43 frequently-used herbs (Frequency≥4) were recorded by Excel table and analyzed by SPSS 18. 0 statistical software. Results: It was found that the medicine commonly used by clinicians in the treatment of Idiopathic Pulmonary Fibrosis ( IPF) are qi-tonifying medicinal, blood-activating and stasis-resolving medicinal, phlegm-resolving medicinal, blood-tonifying medicinal and yin-tonify-ing medicinal. Conclusion:The cluster analysis results showed that the common treatment methods for treating idiopathic pulmo-nary fibrosis are replenishing qi and nourishing yin, activating blood circulation, dispelling phlegm and dredging collaterals.关键词
特发性肺纤维化/中医药疗法/聚类分析/用药规律Key words
Idiopathic pulmonary fibrosis/TCM therapy/Cluster analysis/Medicinal combination rules分类
医药卫生引用本文复制引用
刘耸峰,吕晓东,庞立健,刘创,郑炜东,臧凝子,滑振,赵仲雪..基于聚类分析探究中药复方治疗肺间质纤维化临床用药规律[J].世界中医药,2016,11(7):1370-1373,4.基金项目
国家自然科学基金面上项目(编号:81373579)---基于TGF-β1/Smads信号传导通路的益气养阴活血通络法干预特发性肺纤维化机制研究 （编号:81373579）
辽宁省科技厅计划项目(编号:2012225018-202)---中医治疗优势病种关键技术研究和产品开发 （编号:2012225018-202）
“十二五”国家中医药管理局中医络病重点学科建设项目 （）
辽宁省中医临床重点学(专)科服务能力建设项目(编号:2013-LNZYXZK-2)---基于络病理论“内外同治”防治特发性肺纤维化诊疗方案临床疗效研究 （专）
国家自然科学基金青年基金项目(编号:81403290)---基于肺络构效和肺热络瘀理论的清络饮协调TH1/TH2细胞因子平衡干预特发性肺纤维化机制研究 （编号:81403290）
辽宁省高等学校科学研究一般项目基础究(编号:L2014369) （编号:L2014369）
