摘要
Abstract
Objective To study the therapeutic effect of bifidobaeterium tetravaccine tablets (intestinal probiotics) in the treatment of children’ s noninfectious diarrhea and its influence on the levels of serum IL-6 and IL-17.Methods From March 2014 to February 2014, 68 cases of noninfectious diarrhea in Yulin, Shanxi,traditional Chinese medicine hospital were enrolled, according to the draw method, they were divided into observation group and control group, 34 cases in each group. Control group was treated with conventional treatment, while the observation group was treated with intestinal probiotics on the basis of control group.Total effect, IL-6, IL-17 levels before and after treatment of 7 d were compared, and the improvements of pathogenetic conditions after treatment of two groups patients were observed.Results The total clinical efficacy rate of ob-servation group was 91.18%(31/34), which was significantly higher than the control group of 70.59%(24/34), statistical-ly significant difference ( P <0.05) .After treatment, the serum levels of IL-6, IL-17 in observation group were obviously lower than the control group [(9.47 ±1.01) pg/ml vs.(16.08 ±3.11) pg/ml,(10.47 ±1.14) pg/ml vs.(17.85 ±3.44) pg/ml, P <0.05], the differences were statistically significant ( P <0.05).Observation group of the patient's body temper-ature returned to normal time, diarrhea stop time, hospital stay were all obviously shorter than those of the control group [(3.11 ±0.63) d vs.(6.04 ±1.02)d , (2.21 ±0.31) d vs.(4.24 ±0.63)d , (4.22 ±0.54) d vs.(7.32 ±1.02)d, P <0.05].Conclusion Pediatric infectious diarrhoea taking intestinal probiotics treatment can improve the total effect, sig-nificantly reduce serum level of IL-6, IL-17 and shorten the antidiarrheal time and treatment time, and its clinical curative effect is obviously.关键词
双歧杆菌四联活菌片/非感染性腹泻/IL-6/IL-17/小儿Key words
Bifidobacterium tetravaccine/Noninfectious diarrhea/IL-6/IL-17/Children
