中国当代儿科杂志2016，Vol.18Issue(8)：698-701,4.DOI:10.7499/j.issn.1008-8830.2016.08.005
宁夏地区160 046名新生儿先天性肾上腺皮质增生症筛查与治疗随访分析
Screening and follow-up treatment of 160 046 neonates with congenital adrenal hyperplasia in Ningxia, China
摘要
Abstract
ObjectiveTo investigate the incidence of congenital adrenal hyperplasia (CAH) and treatment outcomes in neonates in Ningxia, China.MethodsThe clinical data of CAH screening for 160 046 neonates who were born in midwifery institutions in Ningxia from July 2014 to March 2016 were analyzed.ResultsAmong the 160 046 neonates who underwent CAH screening, 70 (0.044%) obtained a positive result and 11 were diagnosed with CAH; the incidence rate of CAH was 1/14 550 (0.069‰). Among the 11 neonates diagnosed with CAH, 9 had the salt wasting type (2 died) and 2 had simple virilization. The 9 neonates were given glucocorticoids immediately once diagnosed and all of them achieved good growth and development.ConclusionsThe incidence of neonatal CAH in Ningxia is 1/14 550. It is very necessary to carry out CAH screening in Ningxia, and active treatment can improve the prognosis of neonates with CAH.关键词
先天性肾上腺皮质增生症/17-羟孕酮/新生儿Key words
Congenital adrenal hyperplasia/17-Hydroxyprogesterone/Neonate引用本文复制引用
毛新梅,井淼,田海燕..宁夏地区160 046名新生儿先天性肾上腺皮质增生症筛查与治疗随访分析[J].中国当代儿科杂志,2016,18(8):698-701,4.基金项目
宁夏卫生计生委重点科研计划项目[NW2015-054]。 （）
