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国人冠心病合并糖尿病患者接受雷帕霉素洗脱钴铬合金支架植入术后的长期预后分析

潘月毅 瓦哈甫·马木提 左武旭 杨继娥 张峰 钱菊英 葛雷 周俊 葛均波

中国临床医学2016,Vol.23Issue(3):286-290,5.
中国临床医学2016,Vol.23Issue(3):286-290,5.

国人冠心病合并糖尿病患者接受雷帕霉素洗脱钴铬合金支架植入术后的长期预后分析

Long-term prognosis of cobalt-chromium sirolimus-eluting stent implantation in patients with coronary heart disease complicated with diabetes mellitus

潘月毅 1瓦哈甫·马木提 2左武旭 1杨继娥 1张峰 1钱菊英 1葛雷 1周俊 1葛均波1

作者信息

  • 1. 复旦大学附属中山医院心内科,上海 200032
  • 2. 新疆维吾尔自治区喀什地区第二人民医院心内科,喀什 844000
  • 折叠

摘要

Abstract

Objective:To evaluate the long-term efficacy and safety of a novel type of cobalt-chromium sirolimus-eluting stent (CoCr-SES) in patients with coronary artery disease (CAD) complicated with diabetes mellitus (DM ) .Methods:A total of 1 045 Chinese patients with DM were enrolled into a prospective ,multicenter registered research and followed up for the incidence of death ,myocardial infarction (MI) ,blood circulation reconstruction and thrombosis (ST) among other events . The primary endpoint was a major adverse cardiovascular event (MACE) ,which was composed of cardiovascular death ,non-fatal myocardial infarction (MI) and target vessel revascularization (TVR) ,with a clinical follow-up of 3 years .Results:During the 3-year follow-up ,among 1 045 cases of coronary heart disease complicated with diabetes mellitus ,the rate of MACE was 10 .0% ,including 41 cases (3 .9% ) of cardiovascular death ,38 cases (3 .6% ) of non-fatal MI and 25 cases (2 .4% ) of TVR . The incidence of stent thrombosis (ST ) was 1 .1% in 3 years ,including 7 cases (0 .7% ) of early ST and 4 cases (0 .4% ) of advanced ST .Conclusions:The incidence of MACE and ST is low in patients with coronary heart disease complicated with diabetes at 3 years after implantation of CoCr-SES ,providing compelling evidence for the wide use of domestic CoCr-SES in patients with coronary heart disease complicated with diabetes .

关键词

冠心病/糖尿病/药物洗脱支架/钴铬合金

Key words

coronary artery disease/diabetes mellitus/drug-eluting stent/cobalt-chromium

分类

医药卫生

引用本文复制引用

潘月毅,瓦哈甫·马木提,左武旭,杨继娥,张峰,钱菊英,葛雷,周俊,葛均波..国人冠心病合并糖尿病患者接受雷帕霉素洗脱钴铬合金支架植入术后的长期预后分析[J].中国临床医学,2016,23(3):286-290,5.

基金项目

新疆维吾尔自治区科技支疆项目计划(201591154).Supported by Xinjiang Science and Technology Support Programme of the Xinjiang Uygur Autonomous Region (201591154). ()

中国临床医学

OACSTPCD

1008-6358

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