中国临床医学2016，Vol.23Issue(3)：324-326,3.
七氟醚联合丙泊酚麻醉维持在全麻复合硬膜外麻醉中的临床应用
Application of sevoflurane combined with propofol anesthesia maintenance in general anesthesia combined with epidural anesthesia
梁超 1丁明 1杜芳 1仓静 1薛张纲1
作者信息
- 1. 复旦大学附属中山医院麻醉科，上海 200032
- 折叠
摘要
Abstract
Objective: To compare the effects of propofol combined with sevoflurane on maintenance of general anesthesia with sevoflurane alone for maintenance of anesthesia for patients’ recovery .Methods:160 patients scheduled for gastrointestinal surgery under epidural block combined with general anesthesia were randomly divided into sevoflurane group (group S ,n= 80) and sevoflurane/propofol group (group SP ,n= 80) .After induction ,anesthesia was maintained with sevoflurane in group S and sevoflurane combined with propofol (1 .2 μg/mL) in group SP .Bispectral Index (BIS) values were maintained at 40-60 during the maintenance of anesthesia .The time to extubation ,the incidence of serious cough and agitation during emergence ,and other related events were recorded .Results:The recovery time and the time to extubation in the SP group were (7 .2 ± 2 .0) min and (8 .0 ± 1 .8) min ,respectively ,the recovery time and the time to extubation of the S group were (12 .3 ± 1 .5) min and (12 .8 ± 1 .6) min ,and the difference was statistically significant (P< 0 .05) .The incidence of serious coughing and agitation in SP group (30% and 25% ) were significantly lower than that of group S (68% and 53% ,P<0 .05) .There was no significant difference in BIS value ,the dosage of fentanyl and muscle relaxants during anesthesia between the two groups .Conclusions:Compared with sevoflurane maintenance , sevoflurane combined with propofol for anesthesia maintenance shortens the recovery time and leads to lower incidence of emergence coughing and agitation .关键词
七氟醚/丙泊酚/全身麻醉Key words
propofol/sevoflurane/general anesthesia分类
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梁超,丁明,杜芳,仓静,薛张纲..七氟醚联合丙泊酚麻醉维持在全麻复合硬膜外麻醉中的临床应用[J].中国临床医学,2016,23(3):324-326,3.
