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胸腺切除术后并发重症肌无力危象的救治经验总结

陈群 鲁卫华 秦雪梅 姜小敢 金孝岠

中国全科医学2016,Vol.19Issue(23):2833-2835,2836,4.
中国全科医学2016,Vol.19Issue(23):2833-2835,2836,4.DOI:10.3969/J.issn.1007-9572.2016.23.019

胸腺切除术后并发重症肌无力危象的救治经验总结

Experience Summarization of Treatment of Myasthenia Gravis Crisis After Thymectomy

陈群 1鲁卫华 1秦雪梅 1姜小敢 1金孝岠1

作者信息

  • 1. 241001 安徽省芜湖市,皖南医学院弋矶山医院重症医学科
  • 折叠

摘要

Abstract

Objective To investigate the effective treatment for myasthenia gravis( MG)patients with myasthenia gravis crisis(MC)after thymectomy. Methods From January 2007 to August 2015,six cases with MC after thymectomy who were treated in Department of Critical Care Medicine of YiJishan Hospital,Wannan Medical College,the incentive,treatment experience and prognosis were analyzed retrospectively. Results MC of four patients was triggered by pulmonary infection, among them one improved after treatment,but pulmonary infection got worse after taking away the tube of the life support machine,which triggered brittle crisis;MC of one patient was triggered by not taking medicine according to the instruction,MC of the other one had unclear cause. The six patients were treated by anti - infection treatment at the same time give the pyridostigmine bromide tablets,penehyclidine hydrochloride inJection muscle inJection and glucocorticoids impact treatment, tracheal intubation and mechanical ventilation,and non - invasive helmet mask was used to realize the switching between the invasive ventilation and non - invasive ventilation. After treatment,all MC cases recovered well and were discharged from hospital,the prognosis was good. Conclusion Patients with MG after thymectory may suffer from MC,early mechanical ventilation and accurate invasive - noninvasive sequential switching ventilation,strengthening the respiratory tract management and rational use of medicines can improve the treatment success rate and improve the prognosis.

关键词

重症肌无力/胸腺切除术/重症肌无力危象/急救

Key words

Myasthenia gravis/Thymectomy/Myasthenia gravis crisis/First aid

分类

医药卫生

引用本文复制引用

陈群,鲁卫华,秦雪梅,姜小敢,金孝岠..胸腺切除术后并发重症肌无力危象的救治经验总结[J].中国全科医学,2016,19(23):2833-2835,2836,4.

基金项目

安徽省自然科学基金资助项目(1608085MH199);安徽省卫生厅医学科研项目 ()

中国全科医学

OA北大核心CSTPCD

1007-9572

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