中国药理学通报2016,Vol.32Issue(8):1037-1040,4.DOI:10.3969/j.issn.1001-1978.2016.08.001
乳腺癌免疫治疗新策略
New immunotherapy strategies in breast cancer
摘要
Abstract
Breast cancer is the principal cause of death in malig-nancy women , usually treated with the combination of surgery , chemotherapy , radiotherapy and endocrinotherapy .With the de-velopment of cell biology , molecular biology , immunology, im-munotherapy becomes a new field of breast cancer treatment .In this review, we discuss new findings in breast cancer immuno-therapy , including recent successes with bispecific antibodies and immune checkpoint blockade .We also discuss therapeutic cancer vaccines and highlight several additional immunotherapy modalities in early stages of development .关键词
乳腺癌/免疫治疗/肿瘤疫苗/双特异性抗体/检查点抑制剂/共刺激分子/细胞因子治疗Key words
breast cancer/immunotherapy/cancer vaccines/bispecific antibodies/immune checkpoint blockade/co-stimula-tor/cytokine therapy分类
医药卫生引用本文复制引用
虞林玉,李慕鹏,旷达彬,张聪敏,陈小平..乳腺癌免疫治疗新策略[J].中国药理学通报,2016,32(8):1037-1040,4.基金项目
国家科技部“重大新药创制”科技重大专项( No 2013ZX09509107);国家自然科学基金资助项目( No 81422052,81373489,81170091);湖南省杰出青年基金资助项目 ()