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乳腺癌免疫治疗新策略

虞林玉 李慕鹏 旷达彬 张聪敏 陈小平

中国药理学通报2016,Vol.32Issue(8):1037-1040,4.
中国药理学通报2016,Vol.32Issue(8):1037-1040,4.DOI:10.3969/j.issn.1001-1978.2016.08.001

乳腺癌免疫治疗新策略

New immunotherapy strategies in breast cancer

虞林玉 1李慕鹏 2旷达彬 1张聪敏 2陈小平1

作者信息

  • 1. 中南大学湘雅医院临床药理研究所,湖南长沙 410008
  • 2. 中南大学临床药理研究所,遗传药理学湖南省重点实验室,湖南长沙 410078
  • 折叠

摘要

Abstract

Breast cancer is the principal cause of death in malig-nancy women , usually treated with the combination of surgery , chemotherapy , radiotherapy and endocrinotherapy .With the de-velopment of cell biology , molecular biology , immunology, im-munotherapy becomes a new field of breast cancer treatment .In this review, we discuss new findings in breast cancer immuno-therapy , including recent successes with bispecific antibodies and immune checkpoint blockade .We also discuss therapeutic cancer vaccines and highlight several additional immunotherapy modalities in early stages of development .

关键词

乳腺癌/免疫治疗/肿瘤疫苗/双特异性抗体/检查点抑制剂/共刺激分子/细胞因子治疗

Key words

breast cancer/immunotherapy/cancer vaccines/bispecific antibodies/immune checkpoint blockade/co-stimula-tor/cytokine therapy

分类

医药卫生

引用本文复制引用

虞林玉,李慕鹏,旷达彬,张聪敏,陈小平..乳腺癌免疫治疗新策略[J].中国药理学通报,2016,32(8):1037-1040,4.

基金项目

国家科技部“重大新药创制”科技重大专项( No 2013ZX09509107);国家自然科学基金资助项目( No 81422052,81373489,81170091);湖南省杰出青年基金资助项目 ()

中国药理学通报

OA北大核心CSCDCSTPCD

1001-1978

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