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动脉粥样硬化斑块逆转的研究进展

王姗 孙桂波 罗云 孙晓波

中国药理学通报2016,Vol.32Issue(8):1059-1062,1063,5.
中国药理学通报2016,Vol.32Issue(8):1059-1062,1063,5.DOI:10.3969/j.issn.1001-1978.2016.08.006

动脉粥样硬化斑块逆转的研究进展

Advanced research progress on atherosclerosis plague regression

王姗 1孙桂波 1罗云 1孙晓波1

作者信息

  • 1. 中国医学科学院北京协和医学院药用植物研究所,国家中医药管理局中药干预糖脂代谢紊乱性疾病药效评价重点实验室,中药 天然药物 创新药物研发北京市重点实验室,北京 100193
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摘要

Abstract

Atherosclerosis is the leading cause of death all over the world.Although now many drugs have been widely used for the treatment of the disease , there are still many patients who cannot be cured , especially those with advanced atherosclerosis plague.So the research on the regression of atherosclerosis , es-pecially rapid regression is in need .The research on reverse of atherosclerosis has some breakthrough in recent twenty years , especially in the area of the rapid reversal of advanced plaques , and some new mechanisms have been confirmed , including mac-rophage migration , polarity of macrophages and the relationship between the macrophages and the change of blood lipid , which offers hope for finding more effective drugs in future .

关键词

动脉粥样硬化/动脉粥样硬化逆转/巨噬细胞迁移/巨噬细胞极性转换/高密度脂蛋白/移植

Key words

atherosclerosis/atherosclerosis regression/macro-phage migration/polarity of macrophages/high-density lipopro-tein/transplantation

分类

医药卫生

引用本文复制引用

王姗,孙桂波,罗云,孙晓波..动脉粥样硬化斑块逆转的研究进展[J].中国药理学通报,2016,32(8):1059-1062,1063,5.

基金项目

国家自然科学基金资助项目 ()

中国药理学通报

OA北大核心CSCDCSTPCD

1001-1978

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