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带状疱疹后遗神经痛患者的心理状态和认知功能的变化

俞良 李秀秀 李庆华 陈京凯 周笑一 黄满丽 孙建良

浙江医学2016,Vol.38Issue(15):1257-1259,1262,4.
浙江医学2016,Vol.38Issue(15):1257-1259,1262,4.

带状疱疹后遗神经痛患者的心理状态和认知功能的变化

Changes in psychological status and cognitive functions in patients with postherpetic neuralgia

俞良 1李秀秀 2李庆华 1陈京凯 3周笑一 3黄满丽 3孙建良1

作者信息

  • 1. 310006 杭州市第一人民医院疼痛和麻醉科
  • 2. 浙江大学医学院
  • 3. 浙江大学医学院附属第一医院精神卫生科,浙江省精神障碍诊疗和防治技术重点实验室
  • 折叠

摘要

Abstract

Objective To investigate the changes in psychological status and cognitive functions in patients with postherpetic neuralgia (PHN). Methods Twenty- six patients with PHN and 31 healthy controls were enrol ed in the study. The psychological status and cognition functions were assessed with demographic information questionnaire, simplified McGil pain questionnaire, Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA), Trail Making Test (TMT), digital span memory test, clock drawing test and verbal fluency test. Results The scores of pain rating index (PRI), visual analogue scale (VAS), present pain intensity (PPI)of simplified McGill pain questionnaire in patients with PHN were significantly higher than those of controls (P<0.01). The total scores of HAMD in patients with PHN were significantly higher than those of controls (P<0.01). The total scores of HAMA in patients with PHN were significantly higher than those of controls as wel (P<0.01). The completion time of TMT1 was significantly longer in the PHN patients than that of control subjects (P<0.01). However, no statistical y significant differences were observed in the digital span memory test, clock drawing test and verbal fluency test between two groups. Conclusion PHN patients show higher level of depression and anxiety, severer impairment in attention, and lower speed for information processing, compared to healthy subjects. There are no differences detected in short- term memory, visuospatial function, verbal fluency, and verbal expression skil between PHN patients and normal subjects.

关键词

带状疱疹后遗神经痛/心理状态/认知功能

Key words

Postherpetic neuralgia/Psychological status/Cognitive functions

引用本文复制引用

俞良,李秀秀,李庆华,陈京凯,周笑一,黄满丽,孙建良..带状疱疹后遗神经痛患者的心理状态和认知功能的变化[J].浙江医学,2016,38(15):1257-1259,1262,4.

基金项目

浙江省医药卫生科技项目 ()

浙江医学

OACSTPCD

1006-2785

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