林产化学与工业2016，Vol.36Issue(4)：73-78,6.DOI:10.3969/j.issn.0253-2417.2016.04.010
pH敏感型葡萄糖基水凝胶的制备及溶胀性能测试
Preparation and Swelling Property of pH-Sensitive Glucose-based Hydrogels
摘要
Abstract
Glucose, as the template compound, was modified by glycidyl methacrylate and copolymerized with acrylic acid and acrylamide. After freeze drying, the pH-sensitive glulose-based hydrogels were obtained. The experimental conditions were studied and the optimal conditions were the 1∶4∶4 mass ratio of glucose/acrylic acid/acrylic amide, the 0. 5% dosage of cross-linking agent, initiator and reaction temperature at 65 ℃. And the swelling ratio of hydrogel obtained under these conditions was about 90. 5 g/g. Additionally, it was found that the swelling ratio of the glulose-based hydrogel increased with time extension and finally approached equilibrium in certain pH medium. And the swelling ratio of the hydrogels in the intestinal fluid without enzymes (pH=7. 4) was significantly higher than that in the gastric fluid without enzymes (pH=1. 2). Moreover, the hydrogels could keep basically no degradation in the two kinds of medium. This showed certain application prospect in tissue engineering materials.关键词
水凝胶/pH响应/葡萄糖/溶胀性能Key words
hydrogels/pH-sensitive/glucose/swelling property分类
化学化工引用本文复制引用
林艳,房桂干..pH敏感型葡萄糖基水凝胶的制备及溶胀性能测试[J].林产化学与工业,2016,36(4):73-78,6.基金项目
江苏省生物质能源与材料重点实验室一般项目资助(JSBEM-S-201510) （JSBEM-S-201510）
