特产研究2016,Vol.38Issue(3):18-20,3.DOI:10.16720/j.cnki.tcyj.2016.03.004
牛传染性鼻气管炎IBRV/JZ06-3基础毒株的安全性和免疫原性研究
The Safety and Immunogenicity Study of Infectious Bovine Rhinotracheitis Virus Strain IBRV/JZ06-3
高兵 1苗利光 1朱言柱 1刘艳环 1肖家美 1李海涛1
作者信息
- 1. 中国农业科学院特产研究所,长春 130112
- 折叠
摘要
Abstract
The infectious bovine rhinotracheitis virus strain IBRV/JZ06-3 was used in this study .Single dose ,overdose and single dose redu-plication safety experiment and immunogenicity experiment were adopted in this experiment .When the calves were immunized with IBRV/JZ06-3 ,typical clinical symptoms of infection did not appear .It suggested that the calves immunized with IBRV/JZ06-3 were safe .The mean of SN antibody titters was above 1∶512 in 28d after the immunization .The protection was 100% after challenge .The results suggest that the immu-nization of IBRV/JZ06-3 is safe for the calf ,and it can well protect the calf from the IBRV .关键词
牛传染性鼻气管炎/安全性试验/免疫原性试验Key words
Infectious bovine rhinotracheitis/security test/immunogenicity test分类
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高兵,苗利光,朱言柱,刘艳环,肖家美,李海涛..牛传染性鼻气管炎IBRV/JZ06-3基础毒株的安全性和免疫原性研究[J].特产研究,2016,38(3):18-20,3.