现代医药卫生2016，Vol.32Issue(17)：2656-2657,2.DOI:10.3969/j.issn.1009-5519.2016.17.012
胃泌素释放肽前体和神经元特异性烯醇化酶对小细胞肺癌的诊断价值
Diagnostic value of pro-gastrin-releasing peptide and neuron-specific enolase for small cell lung cancer
朱金秀 1谢强 1钟爱虹 1卢筠 1廖胜祥 1臧焕平 1上官昌吉 2林清华3
作者信息
- 1. 福建医科大学临床教学医院福州肺科医院 肿瘤科，福建福州350008
- 2. 福建医科大学临床教学医院福州肺科医院 检验科，福建福州350008
- 3. 福建医科大学临床教学医院福州肺科医院 病理科，福建福州350008
- 折叠
摘要
Abstract
Objective To evaluate the diagnostic values of pro-gastrin-releasing peptide (ProGRP)and neuron specific enolase(NSE)for small cell lung cancer(SCLC). Methods Serum ProGRP and NSE levels were detected in our hospital from June 2014 to July 2015 in 134 cases of pathologically diagnosed SCLC(SCLC group),126 cases of non small cell lung cancer (NSCLC group),72 cases of pneumonia(pneumonia group) and 54 cases of pulmonary TB. The obtained data were analyzed by using the SAS9.0 software. The inter-group comparison adopted Kruskal-Wallis H test and Nemenyi test. Results The levels of serum Pro-GRP and NSE in the SCLC group were significant higher than those in the NSCLC group ,pneumonia group and pul monary TB group,the difference was statistically significant(P<0.01). The sensitivities of detecting ProGRP and NSE for diagnosing SCLC of were 83.5%and 91.0%respectively ,the specificities were 94.3%and 76.9%respectively. The sensitivity of their com-bined detection could increase to 98.5%. Conclusion Detecting tumor marker ProGRP and NSE has a very important clinical significance in diagnosing SCLC.关键词
癌,小细胞/诊断/肺肿瘤/诊断/胃泌素释放肽/诊断应用Key words
Carcinoma,small cell/diagnosis/Lung neoplasms/diagnosis/Gastrin-releasing peptide/diagnostic use引用本文复制引用
朱金秀,谢强,钟爱虹,卢筠,廖胜祥,臧焕平,上官昌吉,林清华..胃泌素释放肽前体和神经元特异性烯醇化酶对小细胞肺癌的诊断价值[J].现代医药卫生,2016,32(17):2656-2657,2.
