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C5b-9在胃腺癌中表达与疾病的相关性研究

谭丹 曾小琴

局解手术学杂志2016,Vol.25Issue(9):632-635,4.
局解手术学杂志2016,Vol.25Issue(9):632-635,4.DOI:10.11659/jjssx.03E016034

C5b-9在胃腺癌中表达与疾病的相关性研究

Relevant research on expression of C5b-9 and disease in gastric adenocarcinoma

谭丹 1曾小琴2

作者信息

  • 1. 第三军医大学新桥医院急诊科,重庆400037
  • 2. 第三军医大学新桥医院呼吸科,重庆400037
  • 折叠

摘要

Abstract

Objective To evaluate the correlation between the expression of C5b-9 and the gastric carcinoma.Methods In this study, the human gastric adenocarcinoma (HGAC)tissues (n =32 cases)from 32 patients were evaluated by immunohistochemistry and tissue chip.The result was analyzed and evaluated by Multinomial logistic regression and likelihood ratio.Results Multinomial logistic regression and likelihood ratio testing showed that over-expression of C5b-9 in HGAC tissue was significantly correlated with clinical stage (P =0.007) and tumor stage (P =0.005),but not with tumor metastasis,lymphoid nodal status,sex or age.Conclusion C5b-9 can be the criteria of di-agnosis and clinical staging for gastric adenocarcinoma,which may help in diagnosis and assessment disease severity of human gastric carcinoma.

关键词

胃腺癌/补体/C5b-9/临床分期

Key words

gastric carcinoma complement/C5b-9/clinical stages

分类

医药卫生

引用本文复制引用

谭丹,曾小琴..C5b-9在胃腺癌中表达与疾病的相关性研究[J].局解手术学杂志,2016,25(9):632-635,4.

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