中国药房2016，Vol.27Issue(24)：3420-3421,3422,3.DOI:10.6039/j.issn.1001-0408.2016.24.33
近红外光谱法快速鉴别复方鱼腥草片
Study on Quick Identification of Fufang Yuxingcao Tablet by Near-infrared Spectroscopy
鲁艺 1闫研 1闫凯 1刘凯双 1殷果 1王珏 1王铁杰1
作者信息
- 1. 深圳市药品检验研究院/深圳药品质量标准研究重点实验室，广东深圳 518057
- 折叠
摘要
Abstract
OBJECTIVE:To establish a method of quick identification of Fufang yuxingcao tablel(manufactured by A). METH-ODS:NIRDRS was adopted,the near-infrared diffuse reflectance spectrum were recorded by a fiber optic probe,and the conformi-ty test model was established through the consistency index (CI) value and the CI limit comparison method. The spectral range of 9 002-7 497.8 cm-1 ,6 903.8-5 596.4 cm-1 and 5 002.4-4 246.4 cm-1 was selected as the characteristic spectral band ,the spectra were preprocessed by first derivation and vector normalization with 17 smoothing points , and 7.0 was set as the CI value;the characteristic spectrum correlation coefficient model was established through the correlation coefficient method ,the spectral range of 6 200-5 500 cm-1,5 000-4 700 cm-1 was selected as the characteristic spectral band,the spectra were preprocessed by first deri-vation with 17 smoothing points,and 97% was set as the threshold. RESULTS:The above established models can rapidly identify and accurately distinguish Fufang yuxingcao tablet(manufactured by A)from similar products of other manufacturers,the CI value of the validation samples was beyond 7.0,the correlation coefficient(r)were less than 97% compared with the reference sample. CONCLUSIONS:The method is simple and rapid,and can be used for fast screening of Fufang yuxingcao tablet.关键词
近红外光谱/一致性检验/相关系数/复方鱼腥草片/快速鉴别Key words
Near-infrared spectroscopy/Conformity test/Correlation coefficient/Fufang yuxingcao tablet/Quick identification分类
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鲁艺,闫研,闫凯,刘凯双,殷果,王珏,王铁杰..近红外光谱法快速鉴别复方鱼腥草片[J].中国药房,2016,27(24):3420-3421,3422,3.
