中国药理学通报2016，Vol.32Issue(9)：1198-1202,5.DOI:10.3969/j.issn.1001-1978.2016.09.004
基于病证结合肠易激综合征动物模型构建方法及研究思路
Progress and ideas of irritable bowel syndrome animal model construction based on combination of disease and syndrome
摘要
Abstract
Establishment of combination of disease and syndrome animal model is an ideal technology platform in TCM research. Currently, many scholars have prepared matching IBS animal models combined typical animal models with etiology, which em-bodies the advantages of syndrome differentiation and promotes the development of combination disease and syndrome animal model. Even though, there still exists some problems about sub-jective evaluation on syndromes, paying more attention on dis-ease and less on syndromes. Therefore, we should deepen the pathogenesis of diseases and TCM syndromes research on animal model replication and improve the method of construction of combination of disease and syndrome animal model through the biological research of combination of disease and syndrome sys-tem. By this way, the idea of preparation animal models will be more mature and the scientific connotation of TCM will be pres-ented more exactly.关键词
肠易激综合征/病证结合/动物模型/方证相关/系统生物学/研究思路Key words
irritable bowel syndrome( IBS)/combination of dis-ease and syndrome/animal model/relation between formulae and diseases/systemic biology/research idea分类
医药卫生引用本文复制引用
旺建伟,张秋樾,胥风华,叶虹玉,赵文静..基于病证结合肠易激综合征动物模型构建方法及研究思路[J].中国药理学通报,2016,32(9):1198-1202,5.基金项目
国家自然科学基金面上项目( No 81573870) （ No 81573870）
中国博士后科学基金第8批特别资助项目(No 2015T80376) （No 2015T80376）
中国博士后科学基金项目(No 2013M531079) （No 2013M531079）
黑龙江省博士后资助项目( No LBH-Z12246) （ No LBH-Z12246）
黑龙江省自然科学基金(面上项目)(No H2015020) （面上项目）
黑龙江中医药大学优秀创新人才支持计划资助(优秀青年学术带头人)(No 051217) （优秀青年学术带头人）
