解放军医药杂志2016，Vol.28Issue(9)：8-11,4.DOI:10.3969/j.issn.2095-140X.2016.09.003
年龄对妊娠期糖尿病发病风险影响的调查研究
An Investigation Study of Ages on Risk of Gestational Diabetes Mellitus in Pregnant Women
摘要
Abstract
Objective To investigate effect of age on pathogenesy of gestational diabetes mellitus (GDM) in pregnant women. Methods Conditions of age and glycometabolism of 21371 pregnant women, who were given primipari-ty and a single live birth from 2007 to 2015 labor and receiving one-step 75 g oral glucose tolerance test ( OGTT) during 24-32 gestational weeks were retrospectively analyzed. The patients were divided into non GDM ( NGDM ) and GDM groups according to OGTT results, and relationship between pregnant age and glucose levels was evaluated, and effect of pregnant age on pathogenesy of GDM was also analyzed. Results There were 2577 GDM patients, and prevalence rate was 12. 1%. GDM prevalence rate respectively were 0, 5. 1%, 7. 5%, 13. 5%, 30. 4% and 68. 5% when pregnant a-ges were less than 20 years old, 20-25 years old, 26-30 years old, 30-35 years old, 36-40 years old and more than 45 years old. Average age of pregnant women in GDM group (33. 28 ± 5. 36 years old) was significantly higher than (29.67 ±3.58) years old in NGDM group (P <0. 01). During 2007 to 2015 years, average age of GDM pregnant women increased from (32. 57 ± 5. 52) years old to (34. 57 ± 4. 95) years old. Ages of NGDM peak and all pregnant women were 29 years old, while GDM peak age was 31 years old. OGTT results at the time of fasting, 60 and 120 min af-ter OGTT were increased with increased pregnant age in NGDM and GDM groups. Conclusion In recent years, in-creased pregnant age may pay an important role to the high prevalence rate of GDM. It is necessary to pay more attention to the high prevalence rate of GDM in pregnancy women less than 30 years old simultaneously.关键词
糖尿病,妊娠/患病率/孕妇年龄/葡糖耐量试验Key words
Diabetes mellitus, gestational/Prevalence/Pregnant age/Glucose tolerance test分类
医药卫生引用本文复制引用
冯莉,卜艳龙,周玲,代威威,李广琦,刘彦君..年龄对妊娠期糖尿病发病风险影响的调查研究[J].解放军医药杂志,2016,28(9):8-11,4.基金项目
国家自然科学基金(21331001) （21331001）
首都临床特色应用研究与成果推广(Z161100000516010) （Z161100000516010）
北京市自然科学基金资助项目(7122109) （7122109）
