解放军医药杂志2016，Vol.28Issue(9)：65-68,4.DOI:10.3969/j.issn.2095-140X.2016.09.018
宫颈髓外浆细胞瘤临床病理分析并文献复习
Clinicopathologic Analysis of Extramedullary Plasmacytoma in Cervix and a Literature Review
沈小英 1亓岽东 2武鑫瑞 1王慧芳 1许春伟 3吴继华1
作者信息
- 1. 100101 北京，解放军306 医院病理科
- 2. 116001辽宁大连，大连大学附属中山医院肿瘤科
- 3. 100071 北京，军事医学科学院附属医院病理科
- 折叠
摘要
Abstract
Objective To investigate clinicopathological characteristics and differential diagnosis of extramedul-lary plasmacytoma ( EMP) in cervix. Methods Clinical manifestation, medical imaging, histopathological changes, im-munophenotype and gene test of 1 EMP patient in cervix were analyzed, and related literature review was also performed. Results Diffuse distribution of tumor cells mainly made up of mature plasma cells with visible karyokinesis. Immunohis-tochemically staining showed that CD79α, CD38, CD138 and Kappa tumor cells were positive, and Lambda, MUM-1, CD3, CD5, CD20 and EBV were negative. levels of WT1 mRNA and PRAME mRNA were 0. 073% and 0. 080% re-spectively, and breakage and recombinant of IGH gene was positive. Conclusion EMP in cervix is a rare tumor, and its clinical feature and medical imaging are atypical. Its diagnosis mainly relies on clinicopathological characteristics, immu-nophenotype and gene analysis.关键词
浆细胞瘤/病理学,临床/免疫组织化学/诊断,鉴别Key words
Plasmacytoma/Pathology, clinical/Immunohistochemistry/Diagnosis, differential分类
医药卫生引用本文复制引用
沈小英,亓岽东,武鑫瑞,王慧芳,许春伟,吴继华..宫颈髓外浆细胞瘤临床病理分析并文献复习[J].解放军医药杂志,2016,28(9):65-68,4.
