河北医学2016，Vol.22Issue(9)：1409-1411,3.DOI:10.3969/j.issn.1006-6233.2016.09.001
乌司他丁联合胸腺肽对脓毒血症患者免疫调理的临床研究
Clinical Study of Ulinastatin and Thymosin on Immune-modulation in Septic Patients
摘要
Abstract
Objective:To study the clinical effect of immune-modulation therapy of ulinastatin and thy-mosin in the treatment of sepsis. Methods:40 patients with sepsis admitted to ICU from Jan.2009 to Dec.2015 were divided into two groups randomly, therapy group and control group. The control group was given routine therapy, while the therapy group was given routine therapy of thymosin and ulinastatin. The dynamic change of C-reactive protein in therapy group were observed before and after therapy on the 4th and 7th day. The score of MODS and APACHIE-Ⅱwere observed. Results:After treatment, the levels of C-reactive protein and the score of MODS and APACHIE-Ⅱ after therapy on the 4th and 9th day decreased significantly. Conclusion:Treating the patients with thymosin and ulinastatin can raise their immunity,decrease the levels of CRP and A-PACHE Ⅱ and MODS score and improve their prognosis.关键词
脓毒症/乌司他丁/胸腺肽/C反应蛋白/APACHE-Ⅱ评分/MODS评分Key words
Sepsis/Thymosin/Ulinastatin/C-reactive protein/APACHE-Ⅱ score/MODS score引用本文复制引用
韩宇,张素梅,施锐..乌司他丁联合胸腺肽对脓毒血症患者免疫调理的临床研究[J].河北医学,2016,22(9):1409-1411,3.基金项目
国家自然科学基金青年科学基金项目,(编号:81201907) （编号:81201907）
