检验医学与临床2016，Vol.13Issue(19)：2711-2713,3.DOI:10.3969/j.issn.1672-9455.2016.19.006
胱抑素C及同型半胱氨酸在肺癌患者中的水平分析
Study on the levels of cystatin C and homocysteine in lung cancer patients
摘要
Abstract
Objective To explore the significance of serum cystatin C (CysC)and serum homocysteine(Hcy)levels in patients with lung cancer .Methods A total of 104 patients with non-small-cell lung cancer were recruited into study group ,including 52 pa-tients with squamous cell carcinomas and 52 patients with adenocarcinoma .Meanwhile ,32 healthy person were selected as control group .CysC and Hcy levels were detected and analyzed .Results There were no significant differences on CysC and Hcy between squamous cell carcinoma and adenocarcinoma patients(P> 0 .05) ,while there were significant differences on CysC and Hcy between the study group and control group(P< 0 .05) .The difference of CysC between clinical TNM stage Ⅰ /Ⅱ and clinical TNM stageⅢ / Ⅳ had statistical significance(t= - 2 .266 ,P= 0 .026) .However ,there was no significant difference in data of Hcy between clin-ical TNM stage Ⅰ /Ⅱ and clinical TNM stage Ⅲ /Ⅳ (P> 0 .05) .Binary logistic regression analysis showed that CysC and Hcy were not independent risk factors for remote organ metastases ,however ,when lung cancer patients had distant organs metastasis , spearman relativity analysis showed that all data of CysC ,Hcy were positively relativity with organ metastasis numbers(r= 0 .392 , 0 .257 ,P< 0 .05) .Conclusion CysC and Hcy are not independent risk factors for metastasis of lung cancer patients .At the later stages of lung cancer ,Hcy and CysC are correlated with the numbers of organ metastasis .关键词
胱抑素 C/同型半胱氨酸/肺癌/非小细胞肺癌Key words
cystatin C/homocysteine/lung cancer/non-small cell lung cancer引用本文复制引用
周美文,高晓坤,杜荣龙,唐四海,李栩,汪赛兵..胱抑素C及同型半胱氨酸在肺癌患者中的水平分析[J].检验医学与临床,2016,13(19):2711-2713,3.基金项目
国家高技术研究发展计划（863）项目（2014AA022304）。 （）
