摘要
Abstract
Objective To explore the effect of Ziyinhuoxuefang combined with Calcium Dobesilate Capsules on the treatment of simple diabetic retinopathy patients .Methods A total of 248 patients (406 eyes) with simple diabetic retinopathy from October 2012 to October 2015 in Traditional Chinese Medicine Hospital of Xi ′an were randomly divided into control group (124 cases ,208 eyes) and treatment group (124 cases ,198 eyes) .Patients in the control group were given Ziyinhuoxuefang ,while patients in the treatment group were given Ziyinhuoxuefang combined with Calcium Dobesilate Capsules .Vision ,the status of fundus and symp-toms before and after treatment were observed in the two groups .Results The total effective treatment rate of vision in the treat-ment group was 95 .2% ,which was significant higher than 85 .4% in the control group(P< 0 .05) .The total effective treatment rate of fundus in the treatment group was 90 .4% ,which was significant higher than 79 .3% in the control group(P< 0 .05) .The total effective treatment rate of symptoms in the treatment group was 96 .7% ,which was significant higher than 79 .8% in the control group(P< 0 .05) .Serum vascular endothelial growth factor (VEGF) and insulin growth factor(IGF-1)before treatment in the two groups had no significant differences(P> 0 .05) .After treatment ,VEGF and IGF-1 in the two groups were all decreased significant-ly(P< 0 .05) .VEGF and IGF-1 in the treatment group after treatment were significant lower than those of the control group(P<0 .05) .Conclusion Ziyinhuoxuefang combined with Calcium Dobesilate Capsules have significant effect on simple diabetic retinopa-thy patients ,could improve vision ,reduce VEGF and IGF-1 effectively .关键词
滋阴活血/羟苯磺酸钙胶囊/单纯性糖尿病视网膜病变/血管内皮细胞生长因子/胰岛素样生长因子Key words
Ziyinhuoxuefang/Calcium Dobesilate Capsules/simple diabetic retinopathy/background diabetic retinopathy/serum vascular endothelial growth factor/insulin growth factor
