四川医学2016，Vol.37Issue(10)：1106-1109,4.DOI:10.16252/j.cnki.issn1004-0501-2016.10.012
2型糖尿病患者冠脉病变与下肢动脉和颈动脉病变的关系
Relationship between Coronary Artery Disease and Lower Extremity Artery and Carotid Artery Disease in Patients with Type 2 Diabetes Mellitus
张磊 1包明晶 1吴冀川 1李蓬秋 1张学军1
作者信息
- 1. 四川省人民医院内分泌科，四川 成都610072
- 折叠
摘要
Abstract
Objective To investigate the relationship between carotid artery atherosclerosis and coronary artery disease in patients with type 2 diabetes mellitus. Methods Totally 204 cases of type 2 diabetes patients were collected. All patients were per-formed carotid artery and lower extremity artery Doppler ultrasonography and dual source coronary CT. Patients were divided into coronary artery disease group and non-coronary lesion group according to whether the coronary artery had plaque formation or not. Clinical data such as age,sex,blood pressure,smoking history and other clinical data and the results of the laboratory tests of glyco-sylated hemoglobin( HbA 1c ) ,blood lipids and other laboratory tests were collected. The risk factors of coronary artery disease and the relationship between coronary artery disease and peripheral atherosclerosis were analyzed. Results Among 204 patients with type 2diabetes mellitus,there were 143 patients with coronary artery disease and 61 patients with non-coronary artery disease. The two groups were compared,and age,history of hypertension,smoking rate,glycosylated hemoglobin,ankle brachial index,urinary al-bumin / creatinine ratio were significantly different. The incidence of coronary artery disease was significantly higher in patients with lower limb or carotid atherosclerosis than in patients without lower limb or carotid artery atherosclerosis(P<0. 0001). Multi-variate logistic regression analysis showed that age,smoking history,ankle brachial index,carotid atherosclerosis and lower extremi-ty atherosclerosis were the significant risk factors for coronary artery disease. Conclusion For patients with type 2 diabetes melli-tus with carotid or lower extremity atherosclerosis,coronary CT examination should be considered for early diagnosis and interven-tion of coronary artery disease.关键词
2型糖尿病/动脉粥样硬化/双源CTKey words
type 2 diabetes/atherosclerosis/dual source CT分类
医药卫生引用本文复制引用
张磊,包明晶,吴冀川,李蓬秋,张学军..2型糖尿病患者冠脉病变与下肢动脉和颈动脉病变的关系[J].四川医学,2016,37(10):1106-1109,4.
