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鹅掌楸苷和光甘草定协同抗氧化作用研究

冯倩茹 叶柳青 刘园园 龚又明 李红艳 王艳

天津中医药2016,Vol.33Issue(10):624-628,5.
天津中医药2016,Vol.33Issue(10):624-628,5.DOI:10.11656/j.issn.1672-1519.2016.10.12

鹅掌楸苷和光甘草定协同抗氧化作用研究

Study on synergistic antioxidant activities of Liriodendrin and Glabridin

冯倩茹 1叶柳青 2刘园园 2龚又明 1李红艳 3王艳2

作者信息

  • 1. 广东省中医院药学部,广州 510120
  • 2. 天津中医药大学中药学院,天津 300193
  • 3. 南开大学药学院,天津 300071
  • 折叠

摘要

Abstract

Objective] To evaluate the synergistic antioxidant activities of Liriodendrin and Glabridin. [Methods] The DPPH and ABTS radicals scavenging assay were established to detect the synergistic antioxidant activities of components. Isobologram method was also established to study the synergistic result. [Results] There was a synergistic antioxidant effect between Liriodendrin and Glabridin in DPPH radicals scavenging assay when the mass ratio was 3∶1, addictive effect when the mass ratio was 1∶1 and antagonistic effect when the mass ratio was 1∶3. There was a synergistic antioxidant effect between Liriodendrin and Glabridin in ABTS radicals scavenging assay when the mass ratio was 3∶1, 1∶1 and 1∶3. And the synergistic antioxidant effect was 1∶3>1∶1>3∶1. [Conclusion] There was a synergistic antioxidant effect between Liriodendrin and Glabridin according to a certain proportion of compound.

关键词

鹅掌楸苷/光甘草定/协同作用/抗氧化活性

Key words

Liriodendrin/Glabridin/synergistic effect/antioxidant activity

分类

医药卫生

引用本文复制引用

冯倩茹,叶柳青,刘园园,龚又明,李红艳,王艳..鹅掌楸苷和光甘草定协同抗氧化作用研究[J].天津中医药,2016,33(10):624-628,5.

基金项目

西青区科技型中小企业发展专项资金项目(XQK H2013-011)。 ()

天津中医药

OACSTPCD

1672-1519

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