疑难病杂志2016，Vol.15Issue(10)：1010-1015,1019,7.DOI:10.3969/j.issn.1671-6450.2016.10.006
生物反馈对脑卒中后抑郁患者的情绪及压力测试参数的影响
The effects of biofeedback therapy on mood and stress test parameters in patients with post-stroke depression
摘要
Abstract
Objective To investigate the effects of biofeedback therapy on mood and autonomic nervous function im-provement in patients with post-stroke depression, and meanwhile observe the variation of heart rate variability ( HRV) param-eters under stress.Methods Forty-eight patients with post-stroke depression were randomly divided into feedback and control groups.Besides conventional rehabilitation, feedback patients received additional HRV biofeedback therapy.Hamilton De-pression Scale ( HAMD) and Modified Barthel Index ( MBI) were used to compare the efficacy differences of the two groups before and after treatment.We also conducted cognitive stress tests as stressors before and after treatment, and observed HRV variation of the two groups in quiet baseline state, cognitive stress state, and resting state were tracked to compare the thera-peutic effects.Results Compared with the control group, the HAMD retardarce score ( t =-2.10, P =0.04) and HAMD sleep disturbance score ( t =7.88, P =0.01) of the feedback group were significantly improved after treatment;the low fre-quecncy (LF) and heart rate (HR) of the feedback group increased slowly( t =36.13, P =0.02, t =14.88, P =0.01). under the stress conditions; and the HR recovery of the feedback group was faster than the feedback group after rest ( t =27.16, P =0.05).Conclusion HRV biofeedback can improve the HRV parameters and mood in patients with post-stroke depression.Under stress conditions, patients that have received HRV biofeedback therapy can achieve a dynamic balance be-tween sympathetic and parasympathetic nerves,which improved patients’ adaptive capacity to various changes.关键词
心率变异性/生物反馈/脑卒中/抑郁/压力应激Key words
Heart rate variability/Biofeedback/Stroke/Depression/Stress引用本文复制引用
李欣,宋鲁平,邢春晓,陈炘钧,张妍..生物反馈对脑卒中后抑郁患者的情绪及压力测试参数的影响[J].疑难病杂志,2016,15(10):1010-1015,1019,7.基金项目
国家自然科学基金资助项目（81341044）；国家重点基础研究发展计划（863计划）项目（2015AA020102）；中央级公益性科研院所基本科研业务费专项资金项目 （）
