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以中枢神经系统症状为首发 HIV 患者的临床特点

陆杰 陈道文 钱敏 石静萍

中风与神经疾病杂志2016,Vol.33Issue(9):795-798,4.
中风与神经疾病杂志2016,Vol.33Issue(9):795-798,4.

以中枢神经系统症状为首发 HIV 患者的临床特点

Clinical analysis of HIV-Starting with central nervous system lesions in patients

陆杰 1陈道文 1钱敏 1石静萍1

作者信息

  • 1. 南京医科大学附属脑科医院神经内科,江苏南京210029
  • 折叠

摘要

Abstract

Objective The present study aimed to determine clinical presentation of HIV-associated central nervous system lesions in patients as the first presentation.Methods A retrospective study of 39 patients with HIV-associated cen-tral nervous system lesions who were hospitalized at Nanjing Brain Hospital from January 1st 2008 to December 31st 2015 was carried out.Results The mean age of the study population was 40.9 ±9.4 years,and median CD4 count was 55 cells/mm(3) (interquartile range (QR:25 ~105).The most common clinical presentations were headache (87.2%), Weight loss (71.8%), and fever (66.7%).Toxoplasma encephalitis (28.2%), AIDS dementia complex ( ADC) (17.9%),primary central nervous system lymphoma(PCNSL)(15.4%),unexplained encephalitis(15.4%)and Strepto-coccus meningitis (12.8%)、 Tuberculous meningitis (12.8%)、 intracranial space occupying lesion of unknown origin (12.8%)were the leading aetiologies of HIV-associated CNS disease of patients.Conclusion HIV-associated CNS dis-ease is common among HIV patients.CNS symptoms of these diseases are complex and sometimes easy to be misdiagnosed. We should pay attention to screening of anti-HIV antibody.

关键词

艾滋病/神经系统病变/临床表现

Key words

AIDS/Central nervous system lesions/Clinical features

分类

临床医学

引用本文复制引用

陆杰,陈道文,钱敏,石静萍..以中枢神经系统症状为首发 HIV 患者的临床特点[J].中风与神经疾病杂志,2016,33(9):795-798,4.

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