中国药业2016，Vol.25Issue(14)：63-65,3.
左氧氟沙星治疗心力衰竭合并肺部感染的临床研究
Efficacy of Levofloxacin in Treating Patients with Heart Failure and Pulmonary Infection
徐子祺1
作者信息
- 1. 中国人民解放军广州军区武汉总医院，湖北 武汉 430070
- 折叠
摘要
Abstract
Objective To study the clinical efficacy of levofloxacin for patients with heart failure and pulmonary infection and its effect on systemic inflammation and stress response. Methods 80 patients with heart failure and pulmonary infection from February 2014 to February 2016 were divided into the control group (ceftazidime) and the observation group (ceftazidime combined with levofloxacin) according to random number method,40 cases in each group. The clinical efficacy of treatment,pathogen clearance rate on pre- and post-treatment,and the changes of inflammation and stress response indicators in the two groups were compared. Results Compared with the control group,the total effective rate was significantly increased in the observation group ( P ﹤ 0. 05);the pathogen clearance rate on post-treatment was obviously increased in the observation group after treatment( P ﹤ 0. 05);the levels of interleukin-6(IL-6), tumor necrosis factor alpha (TNF-α) and brain natriuretic peptide (BNP) on post-treatment in two groups were significantly de-creased and the level of BNP reduced more obviously on post-treatment in the observation group ( P ﹤ 0. 05). Conclusion Lev-ofloxacin can better eliminate the pathogens for patients with heart failure and pulmonary infection,and reduce the levels of systemic inflammation and stress response.关键词
左氧氟沙星/头孢他啶/心力衰竭/肺部感染Key words
levofloxacin/ceftazidime/heart failure/pulmonary infection分类
医药卫生引用本文复制引用
徐子祺..左氧氟沙星治疗心力衰竭合并肺部感染的临床研究[J].中国药业,2016,25(14):63-65,3.
