中国药业2016,Vol.25Issue(16):23-26,4.
灯盏生脉胶囊联合瑞舒伐他汀治疗高血压合并高脂血症的疗效及对血清炎性因子水平的影响
Efficacy of Dengzhan Shengmai Capsules Combined with Rosuvastatin on Hypertension Com-plicated with Hyperlipidemia and Its Effect on the Level of Serum Inflammatory Factors
王伟 1陈宇岚2
作者信息
- 1. 上海市虹口区欧阳路街道社区卫生服务中心,上海 200081
- 2. 上海市虹口区四川北路街道社区卫生服务中心,上海 200080
- 折叠
摘要
Abstract
Objective To exPlore the clinical efficacy of Dengzhan Shengmai CaPsules combined with Rosuvastatin theraPy for hyPerten-sion comPlicated with hyPerliPidemia and its effect on the levels of hyPer-sensitive C-reactive Protein(hs-CRP)and interleukin(IL)-6. Methods 58 Patients with hyPertension combined hyPerliPidemia from APril 2014 to SePtember 2015 in the hosPital were divided into the control grouP and the research grouP according to the random indicator method,29 cases in each grouP. The control grouP was giv-en Rosuvastatin,while the research grouP was given Dengzhan Shengmai CaPsules combined with Rosuvastatin. The treatment course was 4 months. The blood Pressure,blood liPids and the level of hs-CRP and IL-6 of Patients were measured before and after the treat-ment resPectively. The clinical efficacy and adverse reactions of Patients after treatment were comPared. Results After treatment,the im-Proved situation of blood Pressure and blood liPid in research grouP were better than those of control grouP( P < 0. 05);the levels of serum hs-CRP and IL-6 of two grouPs significantly decreased,meanwhile the levels of hs-CRP and IL-6 of research grouP were significantly lower than those of the control grouP( P < 0. 05);the incidence of adverse reactions of research was 13. 79%,which was significantly lower than 20. 69% of the control grouP( P < 0. 05). Conclusion Dengzhan Shengmai CaPsules combined with rosuvastatin has better clinical efficacy on hyPertension comPlicated with hyPerliPidemia,and reduce the risk of adverse reactions,which is worthy of clinical Promotion.关键词
灯盏生脉胶囊/瑞舒伐他汀/高血压/高脂血症/超敏C反应蛋白/白细胞介素6Key words
Dengzhan Shengmai CaPsules/Rosuvastatin/hyPertension/hyPerliPidemia/hs-CRP/IL-6分类
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王伟,陈宇岚..灯盏生脉胶囊联合瑞舒伐他汀治疗高血压合并高脂血症的疗效及对血清炎性因子水平的影响[J].中国药业,2016,25(16):23-26,4.