吉林大学学报（医学版）2016，Vol.42Issue(5)：985-987,3.DOI:10.13481/j.1671-587x.20160528
成人郎格汉斯细胞组织细胞增生症1例报告及文献复习
Adult Langerhans cell histiocytosis:A case report and literature review
摘要
Abstract
Objective:To study the clinical and pathological features of Langerhans cell histiocytosis (LCH), and to provide the reference for its diagnosis and treatment.Methods:The manifestation of one LCH patient was retrospectively analyzed.The features of the LCH patients were explored by analyzing the results of skin biopsy, radiological test and follow-up.The associated literatures were reviewed.Results:The patient presented the typical symptoms gradually,including polycystic lung,skin ulcer,diabetes insipidus,and lactation.The skin pathological findings showed the densely distributed mononuclear cell infiltration in dermis and the immunohistological staining result showed positive CD1a. The patient was follwed up for 7 years and died of heart and lung failure. Conclusion:LHC has various manifestations and should be confirmed by clinical features,pathological features and imaging examination.The adult patients with multisystem and vital organ involvement suggest the poor prognosis.关键词
郎格汉斯细胞组织细胞增生症/CD1a/尿崩症/免疫组织化学Key words
langerhans cell histiocytosis/CD1a/diabetes insipidus/immunohistochemistry分类
医药卫生引用本文复制引用
温泉,王园园,司鹤南,田亚萍..成人郎格汉斯细胞组织细胞增生症1例报告及文献复习[J].吉林大学学报（医学版）,2016,42(5):985-987,3.基金项目
国家自然科学基金资助课题 （）
