化工进展2016，Vol.35Issue(9)：2656-2662,7.DOI:10.16085/j.issn.1000-6613.2016.09.004
发酵液中乳酸的分离提取研究进展
Advances in separation and purification of lactic acid from fermentation broths
孙启梅 1乔凯 1王领民 1高大成 1王崇辉1
作者信息
- 1. 中国石油化工股份有限公司抚顺石油化工研究院，辽宁抚顺 113001
- 折叠
摘要
Abstract
Lactic acid is the raw material for synthesis of poly-(lactic acid). Biological processes are the main industrial method for lactic acid production. Due to the complex composition of fermentation broth,separation and purification of lactic acid from fermentation broth become the key technologies for biosynthesis. They also determine the quality and yield of lactic acid. In this paper,separation methods of lactic acid from fermentation broth are discussed,including crystallization,esterification, extraction,molecular distillation,membrane separation,adsorption andin situ product removal technology combining fermentation with the above separation methods. However,a single technology cannot efficiently extract lactic acid. It has to combine multiple technologies and improve the process route. One of the methods is to combine efficient integration technologies with the fermentation process,realizing continuous or semi-continuous production. This can improve the productivity and quality of lactic acid,and also form a set of purification processes that are efficient,high-quality, low-pollution,low energy-consuming and also feasible for industrial production.关键词
乳酸/分离/提取/发酵液Key words
lactic acid/separation /purification/fermentation broth分类
化学化工引用本文复制引用
孙启梅,乔凯,王领民,高大成,王崇辉..发酵液中乳酸的分离提取研究进展[J].化工进展,2016,35(9):2656-2662,7.
