检验医学与临床2016，Vol.13Issue(18)：2610-2612,3.DOI:10.3969/j.issn.1672-9455.2016.18.021
血清心型脂肪酸结合蛋白联合心肌肌钙蛋白I在低血糖后心肌损害中的诊断价值
Diagnostic value of H - FABP combined with cTnI in myocardial damage after hypoglycemia
朱晓鸿1
作者信息
- 1. 贵州省遵义市第四人民医院检验科 563000
- 折叠
摘要
Abstract
Objective To investigate the clinical value of heart‐type fatty acid binding protein (H‐FABP) combined with cardiac troponin I(cTnI) in the diagnosis of myocardial damage caused by hypoglycemia .Methods Eighty diabetic patients appearing hypo‐glycemia treated in our hospital from May 2013 to May 2015 were selected as the research subjects and contemporaneous 80 healthy volunteers receiving the physical examination were selected as the control group .Serum in the two groups was collected for detec‐ting H‐FABP and cTnI levels .Results The H‐FABP level at 0 - 2 h in the myocardial damage group was significantly increased . The each index level at 0 - 2 h served as the standard to diagnose the myocardial damage ,which found that the diagnostic efficiency of h‐FABP + cTnI was higher ,its sensitivity ,specificity ,positive predictive value and negative predictive value were 87 .6% , 98 .4% ,79 .8% and 99 .6% respectively ,which were significantly higher than those of single h‐FABP and single cTnI .The myocar‐dial zymogram level at 48 h in the patients with h‐FABP + cTnI group was significantly higher than that of the cTnI group and h‐FABP group ,the difference was statistically significant(P< 0 .05) .Conclusion The combination of h‐FABP and cTnI in the diag‐nosis of myocardial injury is helpful to reduce the missed diagnosis of myocardial injury .关键词
血清心型脂肪酸结合蛋白/心肌肌钙蛋白I/低血糖/心肌损伤Key words
serum heart-type fatty acid binding protein/cardiac troponin I/hypoglycemia/myocardial damage引用本文复制引用
朱晓鸿..血清心型脂肪酸结合蛋白联合心肌肌钙蛋白I在低血糖后心肌损害中的诊断价值[J].检验医学与临床,2016,13(18):2610-2612,3.
