摘要
Abstract
Objective To discuss the effects of different transfusion of platelet combined with cryoprecipitate in patients with massive hemorrhage. Methods Totally 54 cases of massive hemorrhage with massive blood transfusion were chosen as the research object in the Affiliated Hospital of Southwest Medical University between July. 2013 and May. 2016. The patients with only infusion of platelet were set as the platelet group,only infusion of cryoprecipitate as the cryoprecipitate group,and platelet combined with cryoprecipitate as the combined group.Prothrombin time ( PT) , activated partial prothrombin time ( APTT) ,thrombin time ( TT) ,fibrinogen( FIB) and platelet( PLT) were statistically analyzed in patients before infusion of 1h and after infusion of 24h among three groups.And to observe the effect of hemostasis, length of stay and survival rate, and the amount of blood products be transfusion. Results TT, PT and APTT of the combined group in 24h were significantly shorter than the control groups ( ﹤0.001). Compared with platelet group, Fbg was significantly increased ( < 0.001), and PLT was significantly increased ( < 0.001) compared with that of the cryoprecipitate group. In combined group, the average hemostasis time was shorter (3.7±2.2h), the average hemostasis rate was higher (91%), and the hospital stay was shorter (22.5±5.6), and the survival rate was higher (89.29%). Conclusion The treatment of patients with massive hemorrhage in group of platelet combined with cryoprecipitate is more obvious compared to platelet and compared to cryoprecipitate .关键词
出血/凝血/输血/血小板/冷沉淀/联合输注Key words
Hemorrhage/Coagulation/Blood transfusion/Platelet/Cryoprecipitate/Combined infusion
