中国当代儿科杂志2016，Vol.18Issue(10)：984-987,4.DOI:10.7499/j.issn.1008-8830.2016.10.013
肺炎支原体抗体和载量指数在儿童肺炎支原体肺炎诊断中的应用
Application of Mycoplasma pneumoniae antibody and load index in the diagnosis of Mycoplasma pneumoniae pneumonia in children
摘要
Abstract
ObjectiveTo study the role of Mycoplasma pneumoniae (MP) load and antibody measurements in the diagnosis of MP pneumonia.MethodsA total of 115 children with MP pneumonia and 400 healthy children were enrolled. The MP load and total antibody level were measured at different stages, and the MP load index (MPLI) was calculated.ResultsThe cut-off value of MPLI for MP infection was 6.12. MPLI and total antibody titer increased during the course of the disease, while MP-DNA decreased rapidly. Within the same time of blood collection, the group with a higher MP load had a signiifcantly higher total antibody titer than the group with a lower MP load (P<0.05). Within 2 weeks of the course of the disease, the negative antibody group had a significantly higher MPLI than the positive antibody group (P<0.05).ConclusionsMPLI provides a standardized quantitative value of MP-DNA and plays an important role in the early diagnosis of MP infection.关键词
肺炎支原体/肺炎支原体载量指数/总抗体滴度/儿童Key words
Mycoplasma pneumoniae/Mycoplasma pneumoniae load index/Total antibody titer/Child引用本文复制引用
谢辉,李基明,张慧芬,王烨,钟立霖,连清荣,董鸿捌..肺炎支原体抗体和载量指数在儿童肺炎支原体肺炎诊断中的应用[J].中国当代儿科杂志,2016,18(10):984-987,4.基金项目
厦门市科技局计划项目（3502Z20144048）。 （）
