中国普通外科杂志2016，Vol.25Issue(9)：1247-1252,6.DOI:10.3978/j.issn.1005-6947.2016.09.004
壶腹腺癌胰十二指肠切除术后预后相关因素分析
Prognostic factors for adenocarcinoma of the ampulla of Vater after pancreaticoduodenectomy
黄秀芸 1王向阳 1杨瑜明 1吴明浩 1刘展1
作者信息
- 1. 湖南师范大学第一附属医院/湖南省人民医院 消化内科，湖南 长沙 410006
- 折叠
摘要
Abstract
Objective: To investigate the prognostic factors in patients with adenocarcinoma of the ampulla of Vater atfer pancreaticoduodenectomy. <br> Methods: hTe clinical and pathological data of patients with adenocarcinoma of the ampulla of Vater undergoing pancreaticoduodenectomy from January 2007 to December 2014 were reviewed. The influential factors for postoperative survival of the patients were analyzed. <br> Results: In the entire group of patients, the postoperative 1-, 3- and 5-year survival rate was 87.5%, 64.3% and 54.5% respectively. Univariate analysis showed that preoperative level of total bilirubin, direct bilirubin, CEA, CA19-9 and CA242 and degree of tumor differentiation, depth of inifltration, lymphatic metastasis, tumor stage, involvement of pancreas, neural invasion and postoperative adjuvant therapy were inlfuential factors for survival. Multivariate analysis indicated that preoperative CEA level and depth of inifltration were independent prognostic factors (bothP<0.05). <br> Conclusion: Multiple factors are related to the prognosis of patients with adenocarcinoma of the ampulla of Vater atfer pancreaticoduodenectomy, and among them, the CEA level and the depth of inifltration are the most important indicators for estimating the prognosis of the patients.关键词
十二指肠肿瘤/肝胰管壶腹/胰十二指肠切除术/预后Key words
Duodenal Neoplasms/Ampulla of Vater/Pancreaticoduodenectomy/Prognosis分类
医药卫生引用本文复制引用
黄秀芸,王向阳,杨瑜明,吴明浩,刘展..壶腹腺癌胰十二指肠切除术后预后相关因素分析[J].中国普通外科杂志,2016,25(9):1247-1252,6.
