中国比较医学杂志2016,Vol.26Issue(8):30-35,6.DOI:10.3969/j.issn.1671-7856.2016.08.004
复杂性状遗传 CC 小鼠与精准医学研究
Collaborative Cross mice and precision medicine
摘要
Abstract
The individual variability should be considered in precision medicine-prevention and treatment strategies.Medical research using genomics, proteomics, metabolomics, systems analyses, and other modern tools has made big progress.In 2002, the members of the Complex-Trait Consortium proposed to develop a new mouse genetics resource called the Collaborative Cross (CC).The CC is a genetic reference panel of recombinant inbred lines of mice, designed for the dissection of complex traits and gene networks.It will provide a powerful measure for functional studies of biological networks, which will be essential to understand the intricacies of disease processes.关键词
精准医学/CC 小鼠/数量性状定位Key words
Precision medicine/The Collaborative Cross/Quantitative trait locus(QTL)分类
医药卫生引用本文复制引用
杜朋,陈孟毅,李程程,樊飞跃,孟爱民..复杂性状遗传 CC 小鼠与精准医学研究[J].中国比较医学杂志,2016,26(8):30-35,6.基金项目
国家自然科学基金(81573094,81372928);中央科研院所基本业务费(2016ZX310042)。 ()