中国比较医学杂志2016,Vol.26Issue(9):88-92,82,6.DOI:10.3969/j.issn.1671-7856.2016.09.016
ADHD实验动物模型比较研究
A comparative research for experimental animal model of ADHD
摘要
Abstract
Objective To summarize the ADHD animal model and analysis the advantages and disadvantages of various models, providing reference to establish ideal animal model for ADHD and providing new way for the future study of ADHD. Methods Collecting ADHD animal models related literature, analyze the sources of the various models and application scope, summarizes the advantages and disadvantages. Results ADHD model mainly divided into four types:genetic model, the nerve injury model, artificial screening model and environmental adaptability. Four types of model modeling purpose is different, different application scope, advantages and disadvantages with each other. Conclusions According to the relevant evaluation standard, there is no ideal animal model of ADHD. SHR rats is the relatively perfect model. The animal model should be selected according to the purpose of the study screening, establishing the ideal ADHD animal model is the important direction of the current research. direction.关键词
ADHD/动物模型/SHR/多巴胺/理想模型Key words
ADHD/Animal models/SHR/Dopamine/Ideal model分类
医药卫生引用本文复制引用
周荣易,王娇娇,韩新民..ADHD实验动物模型比较研究[J].中国比较医学杂志,2016,26(9):88-92,82,6.基金项目
国家自然科学基金面上项目(81273801)。 ()