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猪流行性腹泻病毒细胞受体研究进展

朱庆贺 苗艳 张鹏宇 王观悦 陈曦 王爽 史同瑞

动物医学进展2016,Vol.37Issue(9):95-98,4.
动物医学进展2016,Vol.37Issue(9):95-98,4.

猪流行性腹泻病毒细胞受体研究进展

Advance in Cellular Receptor of Porcine Epidemic Diarrhea Virus

朱庆贺 1苗艳 1张鹏宇 1王观悦 1陈曦 1王爽 1史同瑞1

作者信息

  • 1. 黑龙江省兽医科学研究所,黑龙江齐齐哈尔 161000
  • 折叠

摘要

Abstract

Porcine epidemic diarrhea virus mainly causes diarrhea in piglets,with morbidity and mortality often reaching 100%,the development of pig industry had been seriously affected.A virus must bind to a receptor on its surface to enter a cell and replicate.It had been confirmed that the cell receptor of porcine epidemic diarrhea virus was porcine aminopeptidase N(pAPN).In order to make a better understand of the pAPN,the structure and the functional domain of the pAPN had been researched.The researchers also worked on screening of phages that display peptides with an affinity to pAPN to inhibit porcine epidemic diarrhea virus infections.To further study of porcine epidemic diarrhea virus and the receptor,the progress on pAPN were reviewed in this article.

关键词

猪流行性腹泻病毒/猪氨基肽酶N/受体

Key words

Porcine epidemic diarrhea virus/porcine aminopeptidase N/receptor

分类

农业科技

引用本文复制引用

朱庆贺,苗艳,张鹏宇,王观悦,陈曦,王爽,史同瑞..猪流行性腹泻病毒细胞受体研究进展[J].动物医学进展,2016,37(9):95-98,4.

基金项目

黑龙江省应用技术研究与开发计划 ()

动物医学进展

OA北大核心CSTPCD

1007-5038

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