南方医科大学学报2016，Vol.36Issue(9)：1303-1305,3.DOI:10.3969/j.issn.1673-4254.2016.09.26
IFN-α2b治疗1年疗效欠佳慢性乙型肝炎患者换用恩替卡韦7年后引发HBsAg血清学转换1例
HBsAg seroconversion after entecavir therapy for 7 years following a poor response to interferon-α2b monotherapy in a HBeAg-negative patient with chronic hepatitis B
李桃源 1陈友鹏1
作者信息
- 1. 暨南大学附属第一医院感染科，广东 广州 510630
- 折叠
摘要
Abstract
We report a rare case of HBsAg seroconversion after 7 years of entecavir therapy in a 48-year-old HBeAg-negative CHB male patient with chronic hepatitis B (CHB). After a poor response to a 48-week interferon-α 2b therapy, the patient received long-term entecavir therapy. Serum ALT levels became normal and HBV DNA viral load was undetectable at the 10th week after commencement of entecavir treatment, and seroconversion of HBsAg was detected after 7 years of entecavir therapy.关键词
慢性乙型肝炎/恩替卡韦/乙肝表面抗体/血清学转换Key words
chronic hepatitis B/entecavir/hepatitis B surface antigen/seroconversion引用本文复制引用
李桃源,陈友鹏..IFN-α2b治疗1年疗效欠佳慢性乙型肝炎患者换用恩替卡韦7年后引发HBsAg血清学转换1例[J].南方医科大学学报,2016,36(9):1303-1305,3.
