国际病理科学与临床杂志2016,Vol.36Issue(8):1167-1170,4.DOI:10.3978/j.issn.2095-6959.2016.08.023
细胞周期调节蛋白在早期自然流产患者绒毛和蜕膜组织中的表达及其与自然流产发生的相关性研究
Expression of cell cycle regulatory proteins in villus and decidual tissue from patients with early abortion and study the correlation of expression and occurrence of spontaneous abortion
钟菊晴 1李海霞2
作者信息
- 1. 湖北医药学院附属人民医院产科,湖北 十堰 442000
- 2. 湖北省十堰市妇幼保健院妇科,湖北 十堰 442000
- 折叠
摘要
Abstract
Objective: To investigate the expression of cell cycle regulatory proteins in villus and decidual tissue from patients with early abortion and study the correlation of expression and occurrence of spontaneous abortion. Methods:Selected 35 females with induced abortion and 35 females with spontaneous abortion, divided them into two groups. Detected the expression of cell cycle regulatory proteins in villus and decidual tissue in both two groups by Western blotting and immunohistochemistry.Results: Expression of cell cycle regulatory proteins from induced abortion group was 75%~85% while spontaneous abortion group was 45%~55%, the difference was statistically signiifcant (P<0.05).Conclusion: Early abortion might be related to the expression of cell cycle regulatory proteins in villus and decidual tissue.关键词
细胞周期调节蛋白/自然流产/蜕膜组织Key words
cell cycle regulatory proteins/spontaneous abortion/decidual tissue引用本文复制引用
钟菊晴,李海霞..细胞周期调节蛋白在早期自然流产患者绒毛和蜕膜组织中的表达及其与自然流产发生的相关性研究[J].国际病理科学与临床杂志,2016,36(8):1167-1170,4.