吉林中医药2016，Vol.36Issue(9)：933-936,4.DOI:10.13463/j.cnki.jlzyy.2016.09.020
柴郁温胆汤及其拆方对产后抑郁模型大鼠血清生化指标的影响
Chaiyuwendan decoction on serum biochemical indicators of postpartum depression model rats
摘要
Abstract
Objective To investigate Chaiyuwendan decoction and its model of depression serum biochemical in-dices of zinc,copper,cortisol,cyclic adenosine phosphate impact resistance,in order to provide an effective basis for the clinical treatment. Methods The 70 rats were randomly selected for the study were divided into seven groups ,namely the normal group,model group,Chaiyuwendan soup group,phlegm group,adjusting blood group,raising the Heart group,maprotiline group,each Group 10,reference Katz stimulation chronic unpredictable stress model of de-pression was prepared by atomic absorption assay of copper,zinc levels using radioimmunoassay of cortisol,cyclic a-denosine monophosphate content,o phthalocyanine complex legal side of serum Calcium(ca2),made of aluminum sulfate determination of inorganic phosphorus(P),serum phosphate nitrobenzene law practice phosphatase(ALP), picric acid hair fasting urine creatinine(Cr). Results The normal group and the model group,the difference was sta-tistically significant(P < 0. 05),and the model group on copper,zinc,cortisol levels of cyclic adenosine monophos-phate,other groups have improved zinc,cortisol levels,Chaiyuwendan decoction group and adjusting blood copper lev-els were lower,the cyclic adenosine monophosphate levels,lower copper maprotiline group,cortisol levels,improved zinc,cyclic AMP levels. Differences were statistically significant(P < 0. 05),normal mice ca2,P,ALP,Cr levels were significantly higher than the model group,the difference was statistically significant(P < 0. 05),and the model group, each other group were improved ca2,P,ALP,Cr level,the difference was statistically significant(P < 0. 05). Conclu-sion Chaiyuwendan decoction before being removed by changing its zinc,copper,cortisol,and other indicators of cy-clic adenosine monophosphate and play a good antidepressant effect.关键词
柴郁温胆汤/产后抑郁模型大鼠/锌/铜/皮质醇/环磷酸腺苷Key words
Chaiyuwendan decoction/postpartum depression model rats/zinc/copper/cortisol/cyclic adenosine monophosphate分类
医药卫生引用本文复制引用
钱玮,申院生..柴郁温胆汤及其拆方对产后抑郁模型大鼠血清生化指标的影响[J].吉林中医药,2016,36(9):933-936,4.基金项目
湖北省卫计委2015年度专项课题（2015HW024）。 （）
